Table 3:

Clusters showing significantly larger activity for the affect-incongruent vs the affect-congruent conditions (emotion-control effect)

Anatomical regionPutative BASidexyzVoxels (n)p valuet value
Whole-brain effects
Congruency effect over groups
Cuneus18R/L−16−9624634<0.0014.85
SPL/Superior occipital gyrus7/19L−30−76342540.0044.37
IFG45/47L−5222−102230.0074.37
Cuneus18R18−98161900.0164.52
Congruency effect for psychopathy group
SPL/superior occipital gyrus7/19R/L8−8238925<0.0014.98
Angular gyrus39/19L−30−72343370.0014.35
Superior temporal gyrus42L−32−3262140.0094.51
SPL7R28−74461580.0344.58
CerebellumL−24−66−381460.0464.63
Negative testosterone modulation of group (psychopathic offenders > healthy control subjects) × congruency interaction
aPFC10R305812391<0.0015.10
Supramarginal gyrus40R54−42543250.0014.66
Caudate nucleusR101022730.0024.69
Putamen/InsulaL−346−101760.0225.22
CerebellumR18−76−381880.0165.09
Negative testosterone modulation of Congruency effect in psychopathy
Supramarginal gyrus40R52−4054657<0.0015.32
Precentral/superior frontal gyrus6R/L62266471<0.0015.65
Caudate nucleusR6642280.0064.28
VOI on bilateral aPFC
Congruency effect over groups10R305814310.0014.46
10L−30581050.0363.43
Congruency effect in healthy control subjects10R325814120.0014.58
10L−3452420.0403.40
Negative testosterone modulation of group (psychopathic offenders > healthy control subjects) × congruency interaction10R305812145<0.0015.10
10L−24566150.0103.87
Negative testosterone modulation of congruency effect in psychopathy10R325610770.0024.34
10L−30588170.0153.74
  • Coordinates are defined in MNI (x, y, z) space. The p values represent the FWE cluster-level corrected values for the whole-brain analyses and FWE voxel-level corrected values for the VOI analyses. IFG, Inferior frontal gyrus; L, left; R, right; SPL, superior parietal lobule.