Table 2:

Statistical table

Figure no.Figure panelDescriptionTestDegrees of freedomF valuep value95% CI
1BRotarod (3–7 months)—effect of ageANOVA—fit model4, 10510.6731<0.0001
1BRotarod (3–7 months)—effect of days × ageANOVA—fit model16, 4204.6269<0.0001
1BRotarod (3–7 months)—effect of genotype × ageANOVA—fit model8, 1052.28180.0271
1BRotarod (3 months)—effect of genotypeOne-way ANOVA2, 392.55090.091
1BRotarod (4 months)—effect of genotypeOne-way ANOVA2, 510.28490.7533
1BRotarod (5 months)—effect of genotypeOne-way ANOVA2, 451.54950.2235
1BRotarod (6 months)—effect of genotypeOne-way ANOVA2, 530.61270.5457
1BRotarod (7 months)—effect of genotypeOne-way ANOVA2, 3712.1937<0.0001
1BRotarod (7 months)—WT × SCA6 84Q/84QTukey-HSD0.000414.17–52.89
1BRotarod (7 months)—SCA6 84Q/84Q × SCA6 84Q/+Tukey-HSD0.000912.74–53.71
1BRotarod (7 months)—WT × SCA6 84Q/+Tukey-HSD0.9994−21.94 to 22.54
2BBalance beam latency, 22 mm (3–7 months)—effect of ageANOVA—fit model4, 1054.72340.0026
2BBalance beam latency, 22 mm (3–7 months)—effect of genotype × ageANOVA—fit model8, 1052.07550.0446
2BBalance beam latency, 22 mm (3 months)—effect of genotypeOne-way ANOVA2, 181.83970.1875
2BBalance beam latency, 22 mm (4 months)—effect of genotypeOne-way ANOVA2, 241.31170.288
2BBalance beam latency, 22 mm (5 months)—effect of genotypeOne-way ANOVA2, 211.86480.1797
2BBalance beam latency, 22 mm (6 months)—effect of genotypeOne-way ANOVA2, 250.17790.838
2BBalance beam latency, 22 mm (7 months)—effect of genotypeOne-way ANOVA2, 177.35890.005
2BBalance beam latency, 22 mm (7 months)—WT × SCA6 84Q/84QTukey-HSD0.01010.78–5.88
2BBalance beam latency, 22 mm (7 months)—SCA6 84Q/84Q × SCA6 84Q/+Tukey-HSD0.0210.46–5.86
2BBalance beam latency, 22 mm (7 months)—WT × SCA6 84Q/+Tukey-HSD0.987−2.76 to 3.11
2CBalance beam latency, 18 mm (3–7 months)—effect of ageANOVA—fit model4, 1052.35820.0398
2CBalance beam latency, 18 mm (3–7 months)—effect of genotype × ageANOVA—fit model8, 1053.09950.0035
2CBalance beam latency, 18 mm (3 months)—effect of genotypeOne-way ANOVA2, 181.80680.1927
2CBalance beam latency, 18 mm (4 months)—effect of genotypeOne-way ANOVA2, 240.00710.9929
2CBalance beam latency, 18 mm (5 months)—effect of genotypeOne-way ANOVA2, 212.00140.1601
2CBalance beam latency, 18 mm (6 months)—effect of genotypeOne-way ANOVA2, 250.71120.5007
2CBalance beam latency, 18 mm (7 months)—effect of genotypeOne-way ANOVA2, 177.46180.0047
2CBalance beam latency, 18 mm (7 months)—WT × SCA6 84Q/84QTukey-HSD0.00831.67–11.43
2CBalance beam latency, 18 mm (7 months)—SCA6 84Q/84Q × SCA6 84Q/+Tukey-HSD0.02430.73–11.06
2CBalance beam latency, 18 mm (7 months)—WT × SCA6 84Q/+Tukey-HSD0.9519−4.95 to 6.26
2DBalance beam latency, 15 mm (3–7 months)—effect of ageANOVA—fit model4, 1051.06910.3756
2DBalance beam latency, 15 mm (3–7 months)—effect of genotype × ageANOVA—fit model8, 1052.02760.05
2DBalance beam latency, 15 mm (3 months)—effect of genotypeOne-way ANOVA2, 183.16140.0666
2DBalance beam latency, 15 mm (4 months)—effect of genotypeOne-way ANOVA2, 240.52490.5982
2DBalance beam latency, 15 mm (5 months)—effect of genotypeOne-way ANOVA2, 210.91720.4151
2DBalance beam latency, 15 mm (6 months)—effect of genotypeOne-way ANOVA2, 250.49090.6178
2DBalance beam latency, 15 mm (7 months)—effect of genotypeOne-way ANOVA2, 174.34470.0299
2DBalance beam latency, 15 mm (7 months)—WT × SCA6 84Q/84QTukey-HSD0.03820.22–8.51
2DBalance beam latency, 15 mm (7 months)—SCA6 84Q/84Q × SCA6 84Q/+Tukey-HSD0.1167−0.77 to 8.00
2DBalance beam latency, 15 mm (7 months)—WT × SCA6 84Q/+Tukey-HSD0.9143−4.01 to 5.51
2EBalance beam latency, 12 mm (3–7 months)—effect of ageANOVA—fit model4, 1051.77630.1391
2EBalance beam latency, 12 mm (3–7 months)—effect of genotype × ageANOVA—fit model8, 1052.18640.0342
2EBalance beam latency, 12 mm (3 months)—effect of genotypeOne-way ANOVA2, 180.43040.6568
2EBalance beam latency, 12 mm (4 months) effect of genotypeOne-way ANOVA2, 241.50080.2431
2EBalance beam latency, 12 mm (5 months) effect of genotypeOne-way ANOVA2, 210.3320.7212
2EBalance beam latency, 12 mm (6 months) effect of genotypeOne-way ANOVA2, 250.49320.6165
2EBalance beam latency, 12 mm (7 months) effect of genotypeOne-way ANOVA2, 175.27340.0165
2EBalance beam latency, 12 mm (7 months)—WT × SCA6 84Q/84QTukey-HSD0.04270.16–10.23
2EBalance beam latency, 12 mm (7 months)—SCA6 84Q/84Q × SCA6 84Q/+Tukey-HSD0.03510.33–9.85
2EBalance beam latency, 12 mm (7 months)—WT × SCA6 84Q/+Tukey-HSD0.9987−5.37 to 5.57
3ABalance beam footslips, 22 mm (3–7 months)—effect of ageANOVA—fit model4, 1052.18330.0759
3ABalance beam footslips, 22 mm (3–7 months)—effect of genotype × ageANOVA—fit model8, 1050.58290.79
3ABalance beam footslips, 22 mm (7 months)—effect of genotypeOne-way ANOVA2, 370.16830.8458
3BBalance beam footslips, 18 mm (3–7 months)—effect of ageANOVA—fit model4, 1051.5890.1827
3BBalance beam footslips, 18 mm (3–7 months)—effect of genotype × ageANOVA—fit model8, 1050.66730.7191
3BBalance beam footslips, 18 mm (7 months)—effect of genotypeOne-way ANOVA2, 371.90980.1624
3CBalance beam footslips, 15 mm (3–7 months)—effect of ageANOVA—fit model4, 1052.18590.0756
3CBalance beam footslips,15 mm (3–7 months)—effect of genotype × ageANOVA—fit model8, 1050.59830.7779
3CBalance beam footslips, 15 mm (7 months)—effect of genotypeOne-way ANOVA2, 370.64980.528
3DBalance beam footslips, 12 mm (3–7 months)—effect of ageANOVA—fit model4, 1052.12590.0827
3DBalance beam footslips, 12 mm (3–7 months)—effect of genotype × ageANOVA—fit model8, 1052.10890.0412
3DBalance beam footslips, 12 mm (3 months)—effect of genotypeOne-way ANOVA2, 390.13750.8719
3DBalance beam footslips, 12 mm (4 months)—effect of genotypeOne-way ANOVA2, 510.21860.8044
3DBalance beam footslips, 12 mm (5 months)—effect of genotypeOne-way ANOVA2, 451.42680.424
3DBalance beam footslips, 12 mm (6 months)—effect of genotypeOne-way ANOVA2, 530.71880.492
3DBalance beam footslips, 12 mm (7 months)—effect of genotypeOne-way ANOVA2, 374.19230.0229
3DBalance beam footslips, 12 mm (7 months)—WT × SCA6 84Q/84QTukey-HSD0.03860.05–2.12
3DBalance beam footslips, 12 mm (7 months)—SCA6 84Q/84Q × SCA6 84Q/+Tukey-HSD0.0796−0.10 to 2.10
3DBalance beam footslips, 12 mm (7 months)—WT × SCA6 84Q/+Tukey-HSD0.984−1.11 to 1.27
4BSwimming latency (3–7 months)—effect of ageANOVA—fit model4, 1051.12570.3484
4BSwimming latency (3–7 months)—effect of genotypeANOVA—fit model2, 1050.03010.9704
4BSwimming latency (3–7 months)—effect of age × genotypeANOVA—fit model8, 1051.85850.0744
4CSwimming kicks (3–7 months)—effect of ageANOVA—fit model4, 1051.89240.1421
4CSwimming kicks (3–7 months)—effect of genotypeANOVA—fit model2, 1051.41780.2468
4CSwimming kicks (3–7 months)—effect of age × genotypeANOVA—fit model8, 1051.63430.1238
4CSwimming kicks (3–7 months)—effect of age × genotype × daysANOVA—fit model16, 2101.8120.0312
4DSwimming kicks 7 months (Day 3 of testing)—SCA6 84Q/84Q × WTTukey-HSD0.03750.07–6.71
4DSwimming kicks 7 months (Day 3 of testing)—SCA6 84Q/84Q × SCA6 84Q/+Tukey-HSD0.04390.09–6.78
4DSwimming kicks 7 months (Day 3 of testing)—SCA6 84Q/+ × WTTukey-HSD>1−3.68 to 3.94
5CStride left hindlimb (4–7 months)—effect of genotypeANOVA-fit model2, 630.14320.8741
5CStride left hindlimb (4 months)—effect of genotypeOne-way ANOVA2, 210.16330.8504
5CStride left hindlimb (6 months)—effect of genotypeOne-way ANOVA2, 250.09460.91
5CStride left hindlimb (7 months)—effect of genotypeOne-way ANOVA2, 170.37290.6942
5DStride right hindlimb (4–7 months)—effect of genotypeANOVA-fit model2, 630.45520.6381
5DStride right hindlimb (4 months)—effect of genotypeOne-way ANOVA2, 210.17010.8447
5DStride right hindlimb (6 months)—effect of genotypeOne-way ANOVA2, 250.17290.8422
5DStride right hindlimb (7 months)—effect of genotypeOne-way ANOVA2, 170.09810.9071
5EStance hindlimb (4–7 months)—effect of genotypeANOVA-fit model2, 631.23410.2981
5EStance hindlimb (4 months)—effect of genotypeOne-way ANOVA2, 210.47250.6299
5EStance hindlimb (6 months)—effect of genotypeOne-way ANOVA2, 250.02380.9765
5EOne-way ANOVA2, 170.50180.6141
5FStride left forelimb (4–7 months)—effect of genotypeANOVA-fit model2, 630.25110.7804
5FStride left forelimb (4 months)—effect of genotypeOne-way ANOVA2, 210.37670.6907
5FStride left forelimb (6 months)—effect ofgenotypeOne-way ANOVA2, 250.50510.6094
5FStride left forelimb (7 months)—effect of genotypeOne-way ANOVA2, 170.45830.6399
5GStride right forelimb (4–7 months)—effect of genotypeANOVA-fit model2, 630.07580.9124
5GStride right forelimb (4 months)—effect of genotypeOne-way ANOVA2, 210.23840.79
5GStride right forelimb (6 months)—effect of genotypeOne-way ANOVA2, 250.20740.7653
5GStride right forelimb (7 months)—effect of genotypeOne-way ANOVA2, 170.25880.775
5HStance forelimb (4–7 months)—effect of genotypeANOVA-fit model2, 630.53120.6042
5HStance forelimb (4 months)—effect of genotypeOne-way ANOVA2, 210.35960.7022
5HStance forelimb (6 months)—effect of genotypeOne-way ANOVA2, 251.22990.3094
5HStance forelimb (7 months)—effect of genotypeOne-way ANOVA2, 170.52720.5996
6AStride left hindlimb (1-2 years)—effect of genotypeANOVA-fit model1, 270.080.7654
6AStride left hindlimb (1 year)—effect of genotypeOne-way ANOVA1, 140.46160.5079
6AStride left hindlimb (2 years)—effect of genotypeOne-way ANOVA1, 130.18930.6707
6BStride right hindlimb (1-2 years)—effect of genotypeANOVA-FIT model1, 270.0020.9704
6BStride right hindlimb (1 year)—effect of genotypeOne-way ANOVA1, 140.22750.6407
6BStride right hindlimb (2 years)—effect of genotypeOne-way ANOVA1, 130.36130.5581
6CStance hindlimb (1-2 years)—effect of genotypeANOVA-fit model1, 270.00010.9871
6CStance hindlimb (1 years)—effect of genotypeOne-way ANOVA1, 140.51780.4836
6CStance hindlimb (2 years)—effect of genotypeOne-way ANOVA1, 130.52020.4835
6DStride left forelimb (1-2 years)—effect of genotypeANOVA-fit model1, 270.01170.9045
6DStride left forelimb (1 year)—effect of genotypeOne-way ANOVA1, 1401
6DStride left forelimb (2 years)—effect of genotypeOne-way ANOVA1, 130.04530.8348
6EStride right forelimb (1-2 years)—effect of genotypeANOVA-fit model1, 270.10490.7559
6EStride right forelimb (1 year)—effect of genotypeOne-way ANOVA1, 140.06920.7963
6EStride right forelimb (2 years)—effect of genotypeOne-way ANOVA1, 130.03080.8635
6FStance forelimb (1-2 years)—effect of genotypeANOVA-fit model1, 270.17420.6841
6FStance forelimb (1 year)—effect of genotypeOne-way ANOVA1, 140.56570.4644
6FStance forelimb (2 years)—effect of genotypeOne-way ANOVA1, 130.00590.94
6ERotarod (1 year)—effect of genotypeOne-way ANOVA1, 3056.012<0.0001
6ERotarod (1 year)—WT × SCA6 84Q/84QTukey-HSD<0.000144.07–77.15
6ERotarod (2 years)—effect of genotypeOne-way ANOVA1, 2833.6153<0.0001
6ERotarod (2 years)—WT × SCA6 84Q/84QTukey-HSD<0.000119.35–40.48
7BPurkinje cell count/100 um (7 months)—effect of genotypeOne-way ANOVA1, 1090.00230.9616
7BPurkinje cell count/100 um (2 years)—effect of genotypeOne-way ANOVA1, 9718.7953<0.0001
7BPurkinje cell count/100 um (2 years)—WT × SCA6 84Q/84QOne-way ANOVA<0.00010.58–1.57
7DMolecular layer length (7 months)—effect of genotypeOne-way ANOVA1, 2030.79180.3746
7DMolecular layer length (2 years)—effect of genotypeOne-way ANOVA1, 18933.1151<0.0001
7DMolecular layer length (2 years)—WT × SCA6 84Q/84QOne-way ANOVA<0.000127.35–55.87
8BDensity of striatal cells (7 months) WT × SCA6 84Q/84QStudent's t-test139 (t ratio)0.36140.7184-