Figure no. | Figure panel | Description | Test | Degrees of freedom | F value | p value | 95% CI |
---|---|---|---|---|---|---|---|

1 | B | Rotarod (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 10.6731 | <0.0001 | |

1 | B | Rotarod (3–7 months)—effect of days × age | ANOVA—fit model | 16, 420 | 4.6269 | <0.0001 | |

1 | B | Rotarod (3–7 months)—effect of genotype × age | ANOVA—fit model | 8, 105 | 2.2818 | 0.0271 | |

1 | B | Rotarod (3 months)—effect of genotype | One-way ANOVA | 2, 39 | 2.5509 | 0.091 | |

1 | B | Rotarod (4 months)—effect of genotype | One-way ANOVA | 2, 51 | 0.2849 | 0.7533 | |

1 | B | Rotarod (5 months)—effect of genotype | One-way ANOVA | 2, 45 | 1.5495 | 0.2235 | |

1 | B | Rotarod (6 months)—effect of genotype | One-way ANOVA | 2, 53 | 0.6127 | 0.5457 | |

1 | B | Rotarod (7 months)—effect of genotype | One-way ANOVA | 2, 37 | 12.1937 | <0.0001 | |

1 | B | Rotarod (7 months)—WT × SCA6 84Q/84Q | Tukey-HSD | 0.0004 | 14.17–52.89 | ||

1 | B | Rotarod (7 months)—SCA6 84Q/84Q × SCA6 84Q/+ | Tukey-HSD | 0.0009 | 12.74–53.71 | ||

1 | B | Rotarod (7 months)—WT × SCA6 84Q/+ | Tukey-HSD | 0.9994 | −21.94 to 22.54 | ||

2 | B | Balance beam latency, 22 mm (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 4.7234 | 0.0026 | |

2 | B | Balance beam latency, 22 mm (3–7 months)—effect of genotype × age | ANOVA—fit model | 8, 105 | 2.0755 | 0.0446 | |

2 | B | Balance beam latency, 22 mm (3 months)—effect of genotype | One-way ANOVA | 2, 18 | 1.8397 | 0.1875 | |

2 | B | Balance beam latency, 22 mm (4 months)—effect of genotype | One-way ANOVA | 2, 24 | 1.3117 | 0.288 | |

2 | B | Balance beam latency, 22 mm (5 months)—effect of genotype | One-way ANOVA | 2, 21 | 1.8648 | 0.1797 | |

2 | B | Balance beam latency, 22 mm (6 months)—effect of genotype | One-way ANOVA | 2, 25 | 0.1779 | 0.838 | |

2 | B | Balance beam latency, 22 mm (7 months)—effect of genotype | One-way ANOVA | 2, 17 | 7.3589 | 0.005 | |

2 | B | Balance beam latency, 22 mm (7 months)—WT × SCA6 84Q/84Q | Tukey-HSD | 0.0101 | 0.78–5.88 | ||

2 | B | Balance beam latency, 22 mm (7 months)—SCA6 84Q/84Q × SCA6 84Q/+ | Tukey-HSD | 0.021 | 0.46–5.86 | ||

2 | B | Balance beam latency, 22 mm (7 months)—WT × SCA6 84Q/+ | Tukey-HSD | 0.987 | −2.76 to 3.11 | ||

2 | C | Balance beam latency, 18 mm (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 2.3582 | 0.0398 | |

2 | C | Balance beam latency, 18 mm (3–7 months)—effect of genotype × age | ANOVA—fit model | 8, 105 | 3.0995 | 0.0035 | |

2 | C | Balance beam latency, 18 mm (3 months)—effect of genotype | One-way ANOVA | 2, 18 | 1.8068 | 0.1927 | |

2 | C | Balance beam latency, 18 mm (4 months)—effect of genotype | One-way ANOVA | 2, 24 | 0.0071 | 0.9929 | |

2 | C | Balance beam latency, 18 mm (5 months)—effect of genotype | One-way ANOVA | 2, 21 | 2.0014 | 0.1601 | |

2 | C | Balance beam latency, 18 mm (6 months)—effect of genotype | One-way ANOVA | 2, 25 | 0.7112 | 0.5007 | |

2 | C | Balance beam latency, 18 mm (7 months)—effect of genotype | One-way ANOVA | 2, 17 | 7.4618 | 0.0047 | |

2 | C | Balance beam latency, 18 mm (7 months)—WT × SCA6 84Q/84Q | Tukey-HSD | 0.0083 | 1.67–11.43 | ||

2 | C | Balance beam latency, 18 mm (7 months)—SCA6 84Q/84Q × SCA6 84Q/+ | Tukey-HSD | 0.0243 | 0.73–11.06 | ||

2 | C | Balance beam latency, 18 mm (7 months)—WT × SCA6 84Q/+ | Tukey-HSD | 0.9519 | −4.95 to 6.26 | ||

2 | D | Balance beam latency, 15 mm (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 1.0691 | 0.3756 | |

2 | D | Balance beam latency, 15 mm (3–7 months)—effect of genotype × age | ANOVA—fit model | 8, 105 | 2.0276 | 0.05 | |

2 | D | Balance beam latency, 15 mm (3 months)—effect of genotype | One-way ANOVA | 2, 18 | 3.1614 | 0.0666 | |

2 | D | Balance beam latency, 15 mm (4 months)—effect of genotype | One-way ANOVA | 2, 24 | 0.5249 | 0.5982 | |

2 | D | Balance beam latency, 15 mm (5 months)—effect of genotype | One-way ANOVA | 2, 21 | 0.9172 | 0.4151 | |

2 | D | Balance beam latency, 15 mm (6 months)—effect of genotype | One-way ANOVA | 2, 25 | 0.4909 | 0.6178 | |

2 | D | Balance beam latency, 15 mm (7 months)—effect of genotype | One-way ANOVA | 2, 17 | 4.3447 | 0.0299 | |

2 | D | Balance beam latency, 15 mm (7 months)—WT × SCA6 84Q/84Q | Tukey-HSD | 0.0382 | 0.22–8.51 | ||

2 | D | Balance beam latency, 15 mm (7 months)—SCA6 84Q/84Q × SCA6 84Q/+ | Tukey-HSD | 0.1167 | −0.77 to 8.00 | ||

2 | D | Balance beam latency, 15 mm (7 months)—WT × SCA6 84Q/+ | Tukey-HSD | 0.9143 | −4.01 to 5.51 | ||

2 | E | Balance beam latency, 12 mm (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 1.7763 | 0.1391 | |

2 | E | Balance beam latency, 12 mm (3–7 months)—effect of genotype × age | ANOVA—fit model | 8, 105 | 2.1864 | 0.0342 | |

2 | E | Balance beam latency, 12 mm (3 months)—effect of genotype | One-way ANOVA | 2, 18 | 0.4304 | 0.6568 | |

2 | E | Balance beam latency, 12 mm (4 months) effect of genotype | One-way ANOVA | 2, 24 | 1.5008 | 0.2431 | |

2 | E | Balance beam latency, 12 mm (5 months) effect of genotype | One-way ANOVA | 2, 21 | 0.332 | 0.7212 | |

2 | E | Balance beam latency, 12 mm (6 months) effect of genotype | One-way ANOVA | 2, 25 | 0.4932 | 0.6165 | |

2 | E | Balance beam latency, 12 mm (7 months) effect of genotype | One-way ANOVA | 2, 17 | 5.2734 | 0.0165 | |

2 | E | Balance beam latency, 12 mm (7 months)—WT × SCA6 84Q/84Q | Tukey-HSD | 0.0427 | 0.16–10.23 | ||

2 | E | Balance beam latency, 12 mm (7 months)—SCA6 84Q/84Q × SCA6 84Q/+ | Tukey-HSD | 0.0351 | 0.33–9.85 | ||

2 | E | Balance beam latency, 12 mm (7 months)—WT × SCA6 84Q/+ | Tukey-HSD | 0.9987 | −5.37 to 5.57 | ||

3 | A | Balance beam footslips, 22 mm (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 2.1833 | 0.0759 | |

3 | A | Balance beam footslips, 22 mm (3–7 months)—effect of genotype × age | ANOVA—fit model | 8, 105 | 0.5829 | 0.79 | |

3 | A | Balance beam footslips, 22 mm (7 months)—effect of genotype | One-way ANOVA | 2, 37 | 0.1683 | 0.8458 | |

3 | B | Balance beam footslips, 18 mm (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 1.589 | 0.1827 | |

3 | B | Balance beam footslips, 18 mm (3–7 months)—effect of genotype × age | ANOVA—fit model | 8, 105 | 0.6673 | 0.7191 | |

3 | B | Balance beam footslips, 18 mm (7 months)—effect of genotype | One-way ANOVA | 2, 37 | 1.9098 | 0.1624 | |

3 | C | Balance beam footslips, 15 mm (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 2.1859 | 0.0756 | |

3 | C | Balance beam footslips,15 mm (3–7 months)—effect of genotype × age | ANOVA—fit model | 8, 105 | 0.5983 | 0.7779 | |

3 | C | Balance beam footslips, 15 mm (7 months)—effect of genotype | One-way ANOVA | 2, 37 | 0.6498 | 0.528 | |

3 | D | Balance beam footslips, 12 mm (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 2.1259 | 0.0827 | |

3 | D | Balance beam footslips, 12 mm (3–7 months)—effect of genotype × age | ANOVA—fit model | 8, 105 | 2.1089 | 0.0412 | |

3 | D | Balance beam footslips, 12 mm (3 months)—effect of genotype | One-way ANOVA | 2, 39 | 0.1375 | 0.8719 | |

3 | D | Balance beam footslips, 12 mm (4 months)—effect of genotype | One-way ANOVA | 2, 51 | 0.2186 | 0.8044 | |

3 | D | Balance beam footslips, 12 mm (5 months)—effect of genotype | One-way ANOVA | 2, 45 | 1.4268 | 0.424 | |

3 | D | Balance beam footslips, 12 mm (6 months)—effect of genotype | One-way ANOVA | 2, 53 | 0.7188 | 0.492 | |

3 | D | Balance beam footslips, 12 mm (7 months)—effect of genotype | One-way ANOVA | 2, 37 | 4.1923 | 0.0229 | |

3 | D | Balance beam footslips, 12 mm (7 months)—WT × SCA6 84Q/84Q | Tukey-HSD | 0.0386 | 0.05–2.12 | ||

3 | D | Balance beam footslips, 12 mm (7 months)—SCA6 84Q/84Q × SCA6 84Q/+ | Tukey-HSD | 0.0796 | −0.10 to 2.10 | ||

3 | D | Balance beam footslips, 12 mm (7 months)—WT × SCA6 84Q/+ | Tukey-HSD | 0.984 | −1.11 to 1.27 | ||

4 | B | Swimming latency (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 1.1257 | 0.3484 | |

4 | B | Swimming latency (3–7 months)—effect of genotype | ANOVA—fit model | 2, 105 | 0.0301 | 0.9704 | |

4 | B | Swimming latency (3–7 months)—effect of age × genotype | ANOVA—fit model | 8, 105 | 1.8585 | 0.0744 | |

4 | C | Swimming kicks (3–7 months)—effect of age | ANOVA—fit model | 4, 105 | 1.8924 | 0.1421 | |

4 | C | Swimming kicks (3–7 months)—effect of genotype | ANOVA—fit model | 2, 105 | 1.4178 | 0.2468 | |

4 | C | Swimming kicks (3–7 months)—effect of age × genotype | ANOVA—fit model | 8, 105 | 1.6343 | 0.1238 | |

4 | C | Swimming kicks (3–7 months)—effect of age × genotype × days | ANOVA—fit model | 16, 210 | 1.812 | 0.0312 | |

4 | D | Swimming kicks 7 months (Day 3 of testing)—SCA6 84Q/84Q × WT | Tukey-HSD | 0.0375 | 0.07–6.71 | ||

4 | D | Swimming kicks 7 months (Day 3 of testing)—SCA6 84Q/84Q × SCA6 84Q/+ | Tukey-HSD | 0.0439 | 0.09–6.78 | ||

4 | D | Swimming kicks 7 months (Day 3 of testing)—SCA6 84Q/+ × WT | Tukey-HSD | >1 | −3.68 to 3.94 | ||

5 | C | Stride left hindlimb (4–7 months)—effect of genotype | ANOVA-fit model | 2, 63 | 0.1432 | 0.8741 | |

5 | C | Stride left hindlimb (4 months)—effect of genotype | One-way ANOVA | 2, 21 | 0.1633 | 0.8504 | |

5 | C | Stride left hindlimb (6 months)—effect of genotype | One-way ANOVA | 2, 25 | 0.0946 | 0.91 | |

5 | C | Stride left hindlimb (7 months)—effect of genotype | One-way ANOVA | 2, 17 | 0.3729 | 0.6942 | |

5 | D | Stride right hindlimb (4–7 months)—effect of genotype | ANOVA-fit model | 2, 63 | 0.4552 | 0.6381 | |

5 | D | Stride right hindlimb (4 months)—effect of genotype | One-way ANOVA | 2, 21 | 0.1701 | 0.8447 | |

5 | D | Stride right hindlimb (6 months)—effect of genotype | One-way ANOVA | 2, 25 | 0.1729 | 0.8422 | |

5 | D | Stride right hindlimb (7 months)—effect of genotype | One-way ANOVA | 2, 17 | 0.0981 | 0.9071 | |

5 | E | Stance hindlimb (4–7 months)—effect of genotype | ANOVA-fit model | 2, 63 | 1.2341 | 0.2981 | |

5 | E | Stance hindlimb (4 months)—effect of genotype | One-way ANOVA | 2, 21 | 0.4725 | 0.6299 | |

5 | E | Stance hindlimb (6 months)—effect of genotype | One-way ANOVA | 2, 25 | 0.0238 | 0.9765 | |

5 | E | One-way ANOVA | 2, 17 | 0.5018 | 0.6141 | ||

5 | F | Stride left forelimb (4–7 months)—effect of genotype | ANOVA-fit model | 2, 63 | 0.2511 | 0.7804 | |

5 | F | Stride left forelimb (4 months)—effect of genotype | One-way ANOVA | 2, 21 | 0.3767 | 0.6907 | |

5 | F | Stride left forelimb (6 months)—effect ofgenotype | One-way ANOVA | 2, 25 | 0.5051 | 0.6094 | |

5 | F | Stride left forelimb (7 months)—effect of genotype | One-way ANOVA | 2, 17 | 0.4583 | 0.6399 | |

5 | G | Stride right forelimb (4–7 months)—effect of genotype | ANOVA-fit model | 2, 63 | 0.0758 | 0.9124 | |

5 | G | Stride right forelimb (4 months)—effect of genotype | One-way ANOVA | 2, 21 | 0.2384 | 0.79 | |

5 | G | Stride right forelimb (6 months)—effect of genotype | One-way ANOVA | 2, 25 | 0.2074 | 0.7653 | |

5 | G | Stride right forelimb (7 months)—effect of genotype | One-way ANOVA | 2, 17 | 0.2588 | 0.775 | |

5 | H | Stance forelimb (4–7 months)—effect of genotype | ANOVA-fit model | 2, 63 | 0.5312 | 0.6042 | |

5 | H | Stance forelimb (4 months)—effect of genotype | One-way ANOVA | 2, 21 | 0.3596 | 0.7022 | |

5 | H | Stance forelimb (6 months)—effect of genotype | One-way ANOVA | 2, 25 | 1.2299 | 0.3094 | |

5 | H | Stance forelimb (7 months)—effect of genotype | One-way ANOVA | 2, 17 | 0.5272 | 0.5996 | |

6 | A | Stride left hindlimb (1-2 years)—effect of genotype | ANOVA-fit model | 1, 27 | 0.08 | 0.7654 | |

6 | A | Stride left hindlimb (1 year)—effect of genotype | One-way ANOVA | 1, 14 | 0.4616 | 0.5079 | |

6 | A | Stride left hindlimb (2 years)—effect of genotype | One-way ANOVA | 1, 13 | 0.1893 | 0.6707 | |

6 | B | Stride right hindlimb (1-2 years)—effect of genotype | ANOVA-FIT model | 1, 27 | 0.002 | 0.9704 | |

6 | B | Stride right hindlimb (1 year)—effect of genotype | One-way ANOVA | 1, 14 | 0.2275 | 0.6407 | |

6 | B | Stride right hindlimb (2 years)—effect of genotype | One-way ANOVA | 1, 13 | 0.3613 | 0.5581 | |

6 | C | Stance hindlimb (1-2 years)—effect of genotype | ANOVA-fit model | 1, 27 | 0.0001 | 0.9871 | |

6 | C | Stance hindlimb (1 years)—effect of genotype | One-way ANOVA | 1, 14 | 0.5178 | 0.4836 | |

6 | C | Stance hindlimb (2 years)—effect of genotype | One-way ANOVA | 1, 13 | 0.5202 | 0.4835 | |

6 | D | Stride left forelimb (1-2 years)—effect of genotype | ANOVA-fit model | 1, 27 | 0.0117 | 0.9045 | |

6 | D | Stride left forelimb (1 year)—effect of genotype | One-way ANOVA | 1, 14 | 0 | 1 | |

6 | D | Stride left forelimb (2 years)—effect of genotype | One-way ANOVA | 1, 13 | 0.0453 | 0.8348 | |

6 | E | Stride right forelimb (1-2 years)—effect of genotype | ANOVA-fit model | 1, 27 | 0.1049 | 0.7559 | |

6 | E | Stride right forelimb (1 year)—effect of genotype | One-way ANOVA | 1, 14 | 0.0692 | 0.7963 | |

6 | E | Stride right forelimb (2 years)—effect of genotype | One-way ANOVA | 1, 13 | 0.0308 | 0.8635 | |

6 | F | Stance forelimb (1-2 years)—effect of genotype | ANOVA-fit model | 1, 27 | 0.1742 | 0.6841 | |

6 | F | Stance forelimb (1 year)—effect of genotype | One-way ANOVA | 1, 14 | 0.5657 | 0.4644 | |

6 | F | Stance forelimb (2 years)—effect of genotype | One-way ANOVA | 1, 13 | 0.0059 | 0.94 | |

6 | E | Rotarod (1 year)—effect of genotype | One-way ANOVA | 1, 30 | 56.012 | <0.0001 | |

6 | E | Rotarod (1 year)—WT × SCA6 84Q/84Q | Tukey-HSD | <0.0001 | 44.07–77.15 | ||

6 | E | Rotarod (2 years)—effect of genotype | One-way ANOVA | 1, 28 | 33.6153 | <0.0001 | |

6 | E | Rotarod (2 years)—WT × SCA6 84Q/84Q | Tukey-HSD | <0.0001 | 19.35–40.48 | ||

7 | B | Purkinje cell count/100 um (7 months)—effect of genotype | One-way ANOVA | 1, 109 | 0.0023 | 0.9616 | |

7 | B | Purkinje cell count/100 um (2 years)—effect of genotype | One-way ANOVA | 1, 97 | 18.7953 | <0.0001 | |

7 | B | Purkinje cell count/100 um (2 years)—WT × SCA6 84Q/84Q | One-way ANOVA | <0.0001 | 0.58–1.57 | ||

7 | D | Molecular layer length (7 months)—effect of genotype | One-way ANOVA | 1, 203 | 0.7918 | 0.3746 | |

7 | D | Molecular layer length (2 years)—effect of genotype | One-way ANOVA | 1, 189 | 33.1151 | <0.0001 | |

7 | D | Molecular layer length (2 years)—WT × SCA6 84Q/84Q | One-way ANOVA | <0.0001 | 27.35–55.87 | ||

8 | B | Density of striatal cells (7 months) WT × SCA6 84Q/84Q | Student's t-test | 139 (t ratio) | 0.3614 | 0.7184 | - |