Table 2

Statistical table

	Data structure	Type of test	Power
a	Natural log of HIF1 alpha protein has a normal and homoscedastic distribution and was used as outcome variable	ANOVA followed by Tukey multiple comparisons of means	Peak EAE vs control = 0.99;Peak EAE vs pre-onset EAE = 0.999;Pre-onset EAE vs Control = 0.10
b	Normal distribution	Holm’s test	0.911
c	Normal distribution	Holm’s test	>0.99
d	Normal distribution	Holm’s test	0.89
e	Natural log of luciferase activity has a normal and homoscedastic distribution and was used as outcome variable	ANOVA followed by Tukey multiple comparisons of means	CFA+PTX vs control = 0.37;MOG+CFA+PTX vs control = 0.99;MOG+CFA+PTX vs CFA+PTX = 0.99
f	Non-normal distribution	Mixed-effects model	0.64
g	Non-normal distribution	Mixed-effects model	0.17
h	Non-normal distribution	Fisher’s exact test	0.06
i	Non-normal distribution	Mixed-effects model	0.46
j	Non-normal distribution	Mixed-effects model	0.08
k	Non-normal distribution	Fisher’s exact test	0.05
l	Normal distribution	Student’s t test	0.18
m	Normal distribution	Student’s t test	0.30
n	Normal distribution	Student’s t test	0.26
o	Normal distribution	Student’s t test with Welch’s correction	0.98
p	Normal distribution	Student’s t test with Holm’s test	0.50
q	Normal distribution	Student’s t test with Holm’s test	0.67
r	Normal distribution	Student’s t test with Holm’s test	0.26
s	Non-normal distribution	Mixed-effects model	0.08
t	Non-normal distribution	Mixed-effects model	0.47
u	Non-normal distribution	Fisher’s exact test	0.06
v	Non-normal distribution	Mixed-effects model	0.61
w	Non-normal distribution	Mixed-effects model	0.03
x	Non-normal distribution	Fisher’s exact test	0.22
y	Normal distribution	ANOVA	HIF-1α^fl/fl vs lysM-Cre:HIF-1α^fl/fl = 0.03;HIF-1α^fl/fl vs GFAP-Cre:HIF-1α^fl/fl = 0.02;lysM-Cre:HIF-1α^fl/fl vs GFAP-Cre:HIF-1α^fl/fl = 0.03

Superscript letters refer to the statistical tests in figures, Results, and Table 1.