Table 2

Statistical table

Data structureType of testPower
aNatural log of HIF1 alpha protein has a normal and homoscedastic distribution and was used as outcome variableANOVA followed by Tukey multiple comparisons of meansPeak EAE vs control = 0.99;Peak EAE vs pre-onset EAE = 0.999;Pre-onset EAE vs Control = 0.10
bNormal distributionHolm’s test0.911
cNormal distributionHolm’s test>0.99
dNormal distributionHolm’s test0.89
eNatural log of luciferase activity has a normal and homoscedastic distribution and was used as outcome variableANOVA followed by Tukey multiple comparisons of meansCFA+PTX vs control = 0.37;MOG+CFA+PTX vs control = 0.99;MOG+CFA+PTX vs CFA+PTX = 0.99
fNon-normal distributionMixed-effects model0.64
gNon-normal distributionMixed-effects model0.17
hNon-normal distributionFisher’s exact test0.06
iNon-normal distributionMixed-effects model0.46
jNon-normal distributionMixed-effects model0.08
kNon-normal distributionFisher’s exact test0.05
lNormal distributionStudent’s t test0.18
mNormal distributionStudent’s t test0.30
nNormal distributionStudent’s t test0.26
oNormal distributionStudent’s t test with Welch’s correction0.98
pNormal distributionStudent’s t test with Holm’s test0.50
qNormal distributionStudent’s t test with Holm’s test0.67
rNormal distributionStudent’s t test with Holm’s test0.26
sNon-normal distributionMixed-effects model0.08
tNon-normal distributionMixed-effects model0.47
uNon-normal distributionFisher’s exact test0.06
vNon-normal distributionMixed-effects model0.61
wNon-normal distributionMixed-effects model0.03
xNon-normal distributionFisher’s exact test0.22
yNormal distributionANOVAHIF-1αfl/fl vs lysM-Cre:HIF-1αfl/fl = 0.03;HIF-1αfl/fl vs GFAP-Cre:HIF-1αfl/fl = 0.02;lysM-Cre:HIF-1αfl/fl vs GFAP-Cre:HIF-1αfl/fl = 0.03
  • Superscript letters refer to the statistical tests in figures, Results, and Table 1.