Electrophysiological and morphological properties of type 1 and type 2 VPCs
| Type 1 (N = 11) | Type 2 (N = 8) | |||||
|---|---|---|---|---|---|---|
| Pre-selection parameterCrossings MCL | 5 ± 0.7 | 1 | ||||
| Neurites | Dendrites | Axon | Dendrites | Axon | ||
| Layers | GL + EPL | GL + EPL | MCL + GCL | GL + EPL | GL + EPL | MCL + GCL |
| Branchpointsd,e | 32 ± 5.5 | 23 ± 2.4* | 17 ± 6.0 | 28 ± 4.4 | 4.1 ± 1.0# | 6.6 ± 2.7# |
| 32 ± 5.5 | 40 ± 6.8* | 28 ± 4.4 | 11 ± 3.1 | |||
| Branch length (µm)f,g | 40 ± 3.4 | 63 ± 5.4# | 68 ± 8.8 | 46 ± 5.3 | 81 ± 11# | 117 ± 29# |
| 40 ± 3.4 | 62 ± 5.9*# | 46 ± 5.3 | 93 ± 12# | |||
| Area neurites (mm2) | 0.05 ± 0.01 | 0.5 ± 0.3 | 0.05 ± 0.01 | 0.11 ± 0.04 | ||
| Area soma (µm2) | 146 ± 25 | 182 ± 26 | ||||
| Location soma | 8 × GL vs. 3 × EPL | 2 × GL vs. 6 × EPL | ||||
| Lateral dendritesc | 3 ± 0.4* | 5 ± 0.3 | ||||
| τ(m), (ms)h | 65 ± 6.9* | 96 ± 6.3 | ||||
| Ri (MΩ) | 530 ± 78.2 | 927 ± 204 | ||||
| Threshold (mV) | −50 ± 1.7 | −48 ± 1.2 | ||||
| AP amplitude (mV) | 76 ± 2.1 | 67 ± 5.6 | ||||
| Last/first spike ratio | 0.73 ± 0.04 | 0.66 ± 0.08 | ||||
| Last/first AHP ratio | 1.1 ± 0.04 | 0.88 ± 0.11 | ||||
Mixed-model ANOVA followed by a post hoc comparison d, e , f, g using Bonferroni correction or t-test for independent samples c, h; * p < 0.05 versus type 2; # p < 0.05 versus dendrites. Data are mean ± SEM.