Table 3.

Data regarding area (nm²), perimeter (nm), and curvature (ratio) of the SAS from synapses on spines and dendritic shafts in control cases and AD patients

Group	Postsynaptic structure	Type of synapse	Area of SAS(nm²; mean ± SEM)	Perimeter of SAS (nm; mean ± SEM)	Curvature of SAS (mean ± SEM)
Control	Spine heads	AS	14,5013 ± 4103	1877 ± 38	0.05 ± 0.001
	Spine heads	SS	81,295 ± 12,011	1380 ± 138	0.05 ± 0.010
	Spine necks	AS	82,219 ± 23,461	1413 ± 255	0.04 ± 0.004
	Spine necks	SS	19,199 ± 0	627.7 ± 0	0.04 ± 0
	Dendritic shafts	AS	115,703 ± 2845	1613 ± 24	0.04 ± 0.001
	Dendritic shafts	SS	76,129 ± 4299	1442 ± 51	0.06 ± 0.005
Alzheimer	Spine heads	AS	135,310 ± 4762	1815 ± 47	0.05 ± 0.002
	Spine heads	SS	50,292 ± 12,137	1014 ± 128	0.06 ± 0.010
	Spine necks	AS	61,658 ± 13,211	1150 ± 119	0.05 ± 0.005
	Spine necks	SS	55,339 ± 0	1269 ± 0	0.11 ± 0
	Dendritic shafts	AS	119,272 ± 3335	1638 ± 32	0.04 ± 0.001
	Dendritic shafts	SS	78,687 ± 5885	1280 ± 50	0.06 ± 0.005

All data are corrected for shrinkage factor. SEM: standard error of the mean.