Table 4.

Proportion of the different shapes of synaptic junctions in control and AD patients

GroupType of synapseMacular synapsesPerforated synapsesHorseshoe-shaped synapsesFragmented synapsesTotal synapses
ControlAS83.8% (2145)11.8% (302)3.8% (98)0.6% (16)100% (2561)
SS83.5% (106)3.9% (5)12.6% (16)0.0% (0)100% (127)
AlzheimerAS81.4% (1558)11.5% (221)5.3% (101)1.8% (35)100% (1915)
SS92.5% (110)6.7% (8)0.8% (1)0.0% (0)100% (119)
  • Data are given as percentages with the absolute number of synapses studied in parentheses. Data for each individual case are represented in Table 4-1.