Table 1:

Statistical analyses

	t	df	p	Mean of vehicle	Mean of Cre-TAT
Welch’s two-sample t tests
Fig. 1F, GCL	3.590	24.96	0.0014**	214.70	146.90
Female	2.510	9.97	0.0310*	197.40	137.80
Male	2.684	12.95	0.0188*	229.5	153.7
Fig. 1F, GL	1.541	24.95	0.1358	63.900	50.090
GCL+GL area	1.100	18.63	0.2851	2.756	2.932
Fig. 1H	0.768	12.57	0.4567	32.390	29.200
Female	0.3007	6.670	0.7728	32.39	30.58
Male	0.7001	4.389	0.5192	32.39	27.82
Fig. 1K	0.028	11.79	0.9782	49.890	49.760
Fig. 1N	2.300	10.03	0.0442*	1706.0	1182.0
Fig. 4E, GCL	3.761	15.72	0.0018**	180.70	120.40
Female	1.593	4.88	0.1734	183.1	130.5
Male	2.593	9.188	0.0286*	178.7	124.9
Fig. 4E, GL	1.688	11.96	0.1172	49.570	39.320

	n of Veh	n of Cre-Tat	p	Mean of vehicle	Mean of Cre-TAT
Mann–Whitney tests
Fig. 1C	21	25	<0.0001****	102.6	40.40
Fig. 4C	84	103	0.3283	44.77	41.25
Fig. 4F, GCL	5	5	0.3095	1.524	2.388
Fig. 4F, GL	5	5	>0.9999	0.933	1.187
Fig. 5A
Efna1	5	7	0.0177*	101.50	153.00
Efna2	5	7	0.2677	100.20	117.40
Epha4	5	7	0.8763	100.30	103.10
Robo2	5	7	0.2020	100.90	90.33
Thbs1	5	7	0.0480*	108.30	164.70
Thbs4	7	7	0.0012**	102.10	179.90
Tnc	7	7	0.0239*	99.02	139.80

	n of Ctrl	n of OTX2	p	Mean of Control	Mean of OTX2
Fig. 5B
Efna1	11	8	0.0003***	102.500	58.680
Efna2	11	8	0.0001***	103.300	52.690
Epha4	11	8	0.0025**	102.600	72.510
Robo2	11	8	0.17740	103.700	81.590
Thbs1	11	8	0.0001***	104.600	50.430
Tnc	12	12	0.0015**	105.800	73.870