Estimates of fixed effects in LMM 3
| CTR | NHD | HD | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROI | β | SE | p | 95% CI | β´ | SE | Adjusted p | 95% CI | β´ | SE | Adjusted p | 95% CI |
| WM | 0.6 | 0.050 | <0.00001 | 0.5-0.7 | −0.07 | 0.06 | 0.44 | −0.2 to 0.04 | −0.25 | 0.06 | <0.00001 | −0.4 to −0.13 |
| Thalamus | 0.06 | 0.007 | <0.00001 | 0.04-0.07 | −0.02 | 0.01 | <0.01 | −0.4 to −0.01 | −0.03 | 0.01 | <0.00001 | −0.05 to −0.02 |
The table includes the results obtained with the LMM 3.1 with random intercept and fixed effect of age, group, and their interaction on V of the ROIs. β´ = βNHD or HD-βCTR. The rate of volume change is expressed as milliliters per year. Average estimated age-dependent growth trajectories obtained in the NHD and HD groups were compared with those of the CTR group, with t test and p values adjusted accordingly.