Daily average ethanol consumption in the two-bottle ethanol choice test
| Two-bottle ethanol choice test | Average ethanol consumption (g/kg/d) | p value |
|---|---|---|
| SA | ||
| 5% ethanol | ||
| WT/WT | 0.952 ± 0.371 (n = 6) | |
| SA/SA | 2.168 ± 1.073 (n = 7) | 0.0240 |
| 10% ethanol | ||
| WT/WT | 1.193 ± 0.483 (n = 5) | |
| SA/SA | 2.199 ± 0.478 (n = 5) | 0.0107 |
| SD | ||
| 5% ethanol | ||
| WT/WT | 0.945 ± 0.487 (n = 7) | |
| SD/SD | 1.375 ± 1.201 (n = 6) | 0.4414 |
| 10% ethanol | ||
| WT/WT | 1.294 ± 0.565 (n = 8) | |
| SD/SD | 1.352 ± 1.197 (n = 8) | 0.5286 |
Volitional ethanol intake was measured in a two-bottle choice test between tap water and 5% or 10% ethanol for three weeks in SA and SD mice. The measured values were divided by the number of days for each or the six measurements to obtain putative daily averages. Data are mean ± SD; p values are comparisons with WT/WT obtained by unpaired two-tailed Welch’s t tests, except for consumption of 10% ethanol in SD/SD mice, which was analyzed by Mann–Whitney U test.