Figure | Data structure | Statistical test | p value |
---|---|---|---|

1A | Dataset with two groups | Log-rank | 0.0001 CI: 95% |

1C | Dataset with two groups | t test | 0.005 CI: 95% |

1D, left | Dataset with two groups | t test | n.s. CI: 95% |

1D, right | Dataset with more than two groups | One-way ANOVA | 0.0001 CI: 95% |

2A | Dataset with more than two groups | One-way ANOVA | n.s. CI: 95% |

2B | Dataset with more than two groups | One-way ANOVA | n.s./0.01 CI: 95% |

2C | Dataset with more than two groups | One-way ANOVA | n.s./0.005 CI: 95% |

2D | Dataset with more than two groups | One-way ANOVA | n.s./0.0001 CI: 95% |

3A | Dataset with two groups | t test^{*} | n.s. CI: 95% |

3B | Dataset with two groups | t test^{*} | n.s. CI: 95% |

3C | Dataset with two groups | t test^{**} | n.s. CI: 95% |

3D | Dataset with two groups | Log-rank | n.s. CI: 95% |

3E | Dataset with two groups | t test* | n.s. CI: 95% |

4A | Dataset with two groups | t test^{*} | n.s. CI: 95% |

4B | Dataset with two groups | t test^{*} | n.s. CI: 95% |

4D | Dataset with two groups | t test^{*} | n.s. CI: 95% |

4E | Dataset with two groups | t test | 0.02 CI: 95% |

4F | Dataset with two groups | t test | 0.03 CI: 95% |

4G | Dataset with two groups | t test^{*} | 0.002 CI: 95% |

4I | Dataset with two groups | t test^{*} | n.s. CI: 95% |

4J | Dataset with two groups | t test^{*} | n.s. CI: 95% |

↵Statistical method and

*p*value for all comparisons is detailed by figure, data structure, and statistical test applied. CI indicates confidence interval. When a*p*value was statistically significant (*p*< 0.05), the exact*p*value is reported. Non-significant data are noted as n.s. * denotes that when multiple*t*tests occurred on a single graph, the relevant condition or age was compared between WT and KO mice tested; ** denotes that the KO was compared to the WT at 0, 60, and 90 min.