Table 2.

Summary of changes for inhibitory connections

Inhibition			Adult		Aged		p values
Input area (μm²)			Mean	Median	Mean	Median	KS test	Ranksum
	All	L2/3	7.90 × 10⁴	7.20 × 10⁴	6.71 × 10⁴	5.52 × 10⁴	0.042	0.12
		L4	1.60 × 10⁴	1.44 × 10⁴	1.15 × 10⁴	8.00 × 10³	0.046	0.007
		L5/6	4.27 × 10⁴	3.68 × 10⁴	3.62 × 10⁴	2.96 × 10⁴	0.18	0.19
			Mean	Median	Mean	Median	KS test	Kruskal–Wallis
	Female	L2/3	8.23 × 10⁴	8.32 × 10⁴	9.16 × 10⁴	8.64 × 10⁴	0.95	1.00
		L4	1.65 × 10⁴	1.44 × 10⁴	1.68 × 10⁴	1.28 × 10⁴	0.69	1.00
		L5/6	3.77 × 10⁴	3.36 × 10⁴	4.87 × 10⁴	4.48 × 10⁴	0.65	0.91
	Male	L2/3	7.61 × 10⁴	6.72 × 10⁴	4.77 × 10⁴	4.48 × 10⁴	0.003	0.031
		L4	1.56 × 10⁴	1.44 × 10⁴	7.28 × 10³	4.80 × 10³	0.003	0.002
		L5/6	4.71 × 10⁴	4.88 × 10⁴	2.64 × 10⁴	1.76 × 10⁴	0.029	0.030
Integration distance (μm)			Mean	Median	Mean	Median	KS test	Ranksum
	All	L2/3	248.9	244.7	251.5	275.9	0.030	0.12
		L4	270.4	282.0	233.3	264.2	0.38	0.40
		L5/6	311.7	347.0	280.8	318.4	0.89	0.36
			Mean	Median	Mean	Median	KS test	Kruskal–Wallis
	Female	L2/3	257.3	245.5	262.5	275.9	0.092	1.00
		L4	286.0	299.2	263.1	298.0	0.94	1.00
		L5/6	305.1	301.1	295.4	335.4	0.66	1.00
	Male	L2/3	241.7	243.2	242.9	274.7	0.32	1.00
		L4	257.1	247.3	210.1	196.4	0.039	1.00
		L5/6	317.3	357.1	269.4	317.3	0.26	0.94
Mean charge (pC)			Mean	Median	Mean	Median	KS test	Ranksum
	All	L2/3	5.64	6.06	4.76	4.61	0.17	0.27
		L4	2.45	1.97	1.32	0.93	0.003	0.001
		L5/6	1.18	1.06	0.99	0.78	0.36	0.18
			Mean	Median	Mean	Median	KS test	Kruskal–Wallis
	Female	L2/3	5.46	5.45	0.18	5.71	0.92	1.00
		L4	2.97	2.20	1.47	1.69	0.15	0.56
		L5/6	1.17	1.06	0.95	0.96	0.97	1.00
	Male	L2/3	5.79	6.53	4.03	3.85	0.007	0.21
		L4	2.01	1.94	1.21	0.70	0.004	0.002
		L5/6	1.20	1.05	1.03	0.72	0.22	0.87
Mean amplitude (pA)			Mean	Median	Mean	Median	KS test	Ranksum
	All	L2/3	82.58	84.93	78.61	73.42	0.43	0.55
		L4	46.64	38.92	31.12	31.97	0.11	0.034
		L5/6	29.20	30.55	27.18	28.70	0.62	0.72
			Mean	Median	Mean	Median	KS test	Kruskal–Wallis
	Female	L2/3	76.49	83.77	98.75	98.11	0.30	0.86
		L4	52.17	36.84	37.48	39.91	0.80	1.00
		L5/6	27.32	28.49	28.51	34.50	0.046	0.42
	Male	L2/3	87.72	90.28	62.88	62.88	0.080	0.055
		L4	41.96	39.32	26.15	26.15	0.032	0.094
		L5/6	30.79	30.70	26.14	26.14	0.009	0.047
Fractional percentage input area (%)			Mean	Median	Mean	Median	KS test	Ranksum
	All	L2/3	56.68	58.14	60.72	57.51	0.36	0.33
		L4	12.35	10.29	9.44	9.73	0.15	0.083
		L5/6	30.98	30.56	29.84	32.36	0.55	0.77
			Mean	Median	Mean	Median	KS test	Kruskal–Wallis
	Female	L2/3	58.73	58.14	62.37	58.23	0.13	1.00
		L4	13.13	11.94	9.90	10.81	0.48	1.00
		L5/6	28.15	29.93	27.74	33.63	0.28	1.00
	Male	L2/3	54.88	56.95	59.42	56.76	0.26	1.00
		L4	11.66	9.18	9.08	7.94	0.078	1.00
		L5/6	33.45	31.04	31.51	32.05	0.26	1.00