Table 3.

Frequency of blinding and randomization in various studies of animal disease models

Disease modeledNumber of papersBlind outcome assessment, # % [95% CI]Randomized group allocation, # % [95% CI]
Alzheimer's disease4289522 [18, 26]6716 [12, 19]
Multiple sclerosis1,11717816 [14, 18]1069 [8, 11]
Parkinson's disease2523815 [11, 20]4016 [12, 21]
Intracerebral bleed884349 [38, 60]2731 [21, 41]
Focal ischemia2608733 [28, 40]10038 [32, 45]
Totals2,14544121 [19, 22]34016 [14, 17]

  • Data from Table 1 of Sena et al., 2014.