N and statistical significance for all electrophysiology experiments
| mCherry | hM4D | hM4D + NaCl | All statistical tests are linear mixed effects models | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| A. | C. | A. | C. | A. | C. | Amplitude | Median Inst. Freq. | Frequency | |||
| L II/III | N | 8 | 42 | 7 | 28 | 5 | 24 | E | (F(2,18.71) = 2.414; p = 0.117) | (F(2,90) = 15.553, p < 0.001)↓ | (F(1,92) = 12.271; p < 0.001)↓ |
| ♂ | 2 | 5 | 3 | I | (F(2,16.30) = 0.269; p = 0.768) | (F(2,17.03) = 0.785; p = 0.472) | (F(2,16.39) = 1.141; p = 0.344) | ||||
| ♀ | 6 | 2 | 2 | E/I | (F(2,5.47) = 1.966; p = 0.173) | (F(2,17.63) = 0.770; p = 0.478) | (F(2,16.55) = 1.196; p = 0.327) | ||||
| II/III→NAc. | N | 5 | 21 | 6 | 28 | – | E | (F(1,6.19) = 3.313; p = 0.117) | (F(1,6.77) = 1.926; p = 0.208) | (F(1,47) = 9.354; p = 0.004)↓ | |
| ♂ | 4 | 4 | I | (F(1,7.03) = 3.402; p = 0.107) | (F(1,7.79) = 0.955; p = 0.358) | (F(1,4.89) = 9.451; p = 0.028)↓ | |||||
| ♀ | 1 | 2 | E/I | (F(1,6.59) = 0.543; p = 0.487) | (F(1,7.91) = 0.836; p = 0.388) | (F(1,8.10) = 0.750; p = 0.411) | |||||
| V/VI→MD | N | 4 | 19 | 5 | 26 | – | E | (F(1,5.36) = 0.689; p = 0.442) | (F(1,6.10) = 13.045; p = 0.011)↓ | (F(1,6.73) = 12.960; p = 0.009)↓ | |
| ♂ | 1 | 3 | I | (F(1,4.77) = 0.991; p = 0.367) | (F(1,5.96) = 6.501; p = 0.044)↓ | (F(1,6.39) = 7.829; p = 0.029)↓ | |||||
| ♀ | 3 | 2 | E/I | (F(1,42) = 3.625; p = 0.064) | (F(1,5.21) = 0.975; p = 0.367) | (F(1,5.31) = 1.115; p = 0.337) | |||||
| V/VI→NAc. | N | 5 | 22 | 4 | 9 | – | E | (F(1,29) = 8.976; p = 0.006)↑ | (F(1,6.24) = 0.196; p = 0.673) | (F(1,5.49) ≤ 0.001; p = 0.993) | |
| ♂ | 4 | 2 | I | (F(1,4.25) = 14.809; p = 0.013)↑ | (F(1,6.53) = 0.910; p = 0.374) | (F(1,6.82) = 0.417; p = 0.539) | |||||
| ♀ | 1 | 2 | E/I | (F(1,28) = 2.220; p = 0.147) | (F(1,12.33) = 0.412; p = 0.533) | (F(1,12.10) = 0.014; p = 0.908) | |||||
| II/III→II/III | N | 5 | 38 | 5 | 26 | – | E | (F(1,6.37) = 2.865; p = 0.134) | (F(1,7.30) = 0.399; p = 0.547) | (F(1,7.41) = 0.012; p = 0.917) | |
| ♂ | 2 | 2 | I | (F(1,62) = 0.112; p = 0.912) | (F(1,5.95) = 8.023; p = 0.030)↑ | (F(1,7.32) = 4.185; p = 0.078)↑ | |||||
| ♀ | 3 | 3 | E/I | (F(1,59) = 1.099; p = 0.299) | (F(1,9.34) = 5.744; p = 0.039)↓ | (F(1,11.37) = 5.697; p = 0.035)↓ | |||||
A, animal; C, cell; all significant results are bolded and italicized with directionality indicated by an arrow.