Table 1.

Anxiety index and bouts through the center were computed using three-way mixed-effects models, while rotarod data using the mouse dowel (r = 1.5 cm) and rat dowel (r = 3.5 cm) was computed using three-way ANOVAs

Behavioral outcome	Factors	F (DF_n, DF_d)	p-value
Anxiety index	Vehicle versus CGRP	F_{(1.00, 31.00)} = 1.55	n.s.
	Pre- versus post-OVAR	F_{(1.00, 31.00)} = 58.50	p < 0.0001
	Male versus female	F_{(1.00, 14.00)} = 0.80	n.s.
Bouts through center	Vehicle versus CGRP	F_{(1.00, 31.00)} = 0.47	n.s.
	Pre- versus post-OVAR	F_{(1.00, 31.00)} = 188.00	p < 0.0001
	Male versus female	F_{(1.00, 14.00)} = 3.74	n.s.
Rotarod—mouse dowel	Vehicle versus CGRP	F_{(1.00, 18.00)} = 29.07	p < 0.0001
	Pre- versus post-OVAR	F_{(1.00, 18.00)} = 0.07	n.s.
	Male versus female	F_{(1.00, 18.00)} = 0.17	n.s.
Rotarod—rat dowel	Vehicle versus CGRP	F_{(1.00, 37.00)} = 0.17	n.s.
	Pre- versus post-OVAR	F_{(1.00, 37.00)} = 21.03	p < 0.0001
	Male versus female	F_{(1.00, 37.00)} = 1.88	n.s.

For all multivariate analyses, we examined the following three factors: treatment (i.p. vehicle vs i.p. CGRP), VC (pre- vs post-OVAR), and biological sex (male vs female). F-values are listed with respect to degrees of freedom (DF_n, DF_d) and p-values are listed accordingly.