MNI coordinates, cluster sizes, and significance values for clusters showing midbrain PAG connectivity differences during spontaneous low- versus high-pain intensity blocks in fluctuating pain participants (n = 13)
| Region | MNI coordinate | Cluster size (kE) | t value | z value | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| Highest > lowest pain | ||||||
| Ipsilateral posterior insula | −36 | −32 | 8 | 21 | 6.08 | 4.03 |
| PCC | −6 | −36 | 30 | 18 | 5.16 | 3.68 |
| Ipsilateral hippocampus | −52 | 0 | 2 | 11 | 3.86 | 3.05 |
| Ipsilateral dlPFC | −20 | 34 | 28 | 11 | 3.77 | 3.00 |
| Highest < lowest pain | ||||||
| sgACC | 6 | −28 | −6 | 12 | 3.86 | 3.05 |