Table 7.

Normalized averaged fEPSP amplitudes during high-frequency stimulation at 25 Hz

TrainMeasureWT animalsSynTKO animals
First train 25th stimulusMedian3.7043.653
Interquartile range[1.873; 7.935][2.426; 7.092]
p value (Mann–Whitney U test)p = 0.695
First train 125th stimulusMedian1.2430.7514
Interquartile ranges[0.473; 2.332][0.4997; 1.650]
p value (Mann–Whitney U test)p = 0.74
Fourth train 25th stimulusMedian3.1761.61
Interquartile ranges[1.039; 3.77][0.75; 4.314]
p value (Mann–Whitney U test)p = 0.88
Fourth train 125th stimulusMedian0.6870.3714
Interquartile ranges[0.501; 1.987][0.049; 0.72]
p value (Mann–Whitney U test)p = 0.032
  • Amplitudes were measured in both genotypes in the first and fourth train of 125 pulses at 25 Hz (Fig. 2) at the 25th and 125th stimulus, and their ranks were compared in Mann–Whitney U tests.