Average ± SEM for three morphological metrics included in the cluster analysis: cell body (CB) area (z-scored), cell body position as percent depth in layer 6 (L6) where larger values indicate deeper position closer to the white matter, and height of the apical dendrite (AD) as percent depth in the cortical layers where smaller values indicate shallower position closer to layer 1
| CB area (µm2) | CB position in L6 | AD height | |
|---|---|---|---|
| Cluster 1 (n = 23) | 0.36 ± 0.21 | 41.0 ± 4.2 | 76.9 ± 1.4 |
| Cluster 2 (n = 22) | 0.64 ± 0.29 | 19.3 ± 2.1 | 63.7 ± 2.8 |
| Cluster 3 (n = 22) | 0.03 ± 0.23 | 21.5 ± 2.6 | 24.0 ± 3.0 |
| Cluster 4 (n = 7) | −0.14 ± 0.21 | 11.1 ± 1.3 | 46.2 ± 3.6 |
| Cluster 5 (n = 25) | 0.08 ± 0.16 | 18.8 ± 2.5 | 7.6 ± 1.7 |
| Cluster 6 (n = 13) | −0.76 ± 0.10 | 59.0 ± 2.0 | 6.8 ± 0.8 |
| Cluster 7 (n = 24) | −0.31 ± 0.16 | 69.8 ± 3.2 | 34.8 ± 3.2 |
| Cluster 8 (n = 14) | −0.48 ± 0.15 | 50.7 ± 6.3 | 33.3 ± 4.3 |
| p values | 5.8 × 10−5 | 1.2 × 10−17 | 1.2 × 10−23 |
| Differences | 1,2,3,5 > 6 | 1 > 2,4,5; 6,7,8 > 2,3,4,5 | 1 > 3,5,6,7,8; 2 > 3,5,6,8; 4,7 > 5,6 |
p values for statistical differences across clusters are Bonferroni corrected for multiple comparisons at α = 0.0045; Significant differences between clusters are also listed below.