Summary of the descriptive statistics and results of the Genotype × Sex ANOVAs conducted on the data from the alternate indices of spatial memory recall obtained during Morris water maze testing of Homer2AA/AA, GRM5AA/AA, and GRM5R/R mutants and their WT mice
| Study: | Homer2AA/AA | GRM5AA/AA | GRM5R/R | |||
|---|---|---|---|---|---|---|
| Genotype: | WT(n = 19)(10 F, 9 M) | Mutant(n = 19)(10 F, 9 M) | WT(n = 19)(12 F, 7 M) | Mutant(n = 31)(17 F, 14 M) | WT(n = 19)(12 F, 7 M) | Mutant(n = 29)(13 F, 16 M) |
| Latency to enter former platform location (s) | 15.4 ± 4.2 | 11.5 ± 2.8 | 15.9 ± 2.1 | 10.8 ± 1.3 | 12.3 ± 3.2 | 12.6 ± 2.7 |
| All ps > 0.45 | Genotype: p = 0.10 Sex: F(1,49) = 7.64, p = 0.008 Interaction: p = 0.46 | All ps > 0.64 | ||||
| Time in former quadrant (s) | 24.0 ± 2.6 | 23.8 ± 1.9 | 24.5 ± 1.6 | 26.4 ± 0.9 | 24.0 ± 1.3 | 24.0 ± 1.0 |
| All ps > 0.50 | All ps > 0.13 | All ps > 0.13 | ||||
| Number of former platform location entries | 5.1 ± 0.7 | 5.9 ± 0.7 | 8.2 ± 0.8 | 11.0 ± 0.7 | 7.9 ± 1.2 | 9.6 ± 1.1 |
| All ps > 0.15 | Genotype: F(1,49) = 5.62, p = 0.02 Other ps > 0.49 | All ps > 0.35 | ||||
| Total distance (m) | 16.0 ± 1.0 | 16.2 ± 1.5 | 13.0 ± 1.0 | 13.5 ± 0.7 | 16.6 ± 1.1 | 16.9 ± 0.8 |
| Sex: F(1,37) = 6.40, p = 0.02 Other ps > 0.55 | All ps > 0.27 | All ps > 0.27 | ||||
The data represent the means ± SEMs of the number of mice indicated in parentheses. The number of female (F) and male (M) mice for each genotype is also indicated in parentheses. *p < 0.05 versus WT.