Table 2

Summary of results

		Diazepam			MK-801
		Auditory	Parietal	Frontal	Auditory	Parietal	Frontal
Power Spectrum		↑ Beta oscillations (∼10–20 Hz) ↑ Slow frequencies (∼0.1–10 Hz) ↓ High frequencies (∼60–150 Hz)			↓ Beta oscillations (∼10–20 Hz) ↑ Gamma oscillations (∼30–100 Hz) Appearance of HFO (∼150 Hz)
Aperiodic		↑↑↑ Slope in all regions ↑↑↑ Offset in all regions ↑↑ Knee in all regions			↑ Slope in all regions
					∼ Offset	↑ Offset	∼ Offset
					↑↑↑ Knee in all regions
Periodic	Theta	↓ Amp ↓ AUC	↓↓↓ Amp ↓↓ AUC	∼ Amp ∼ AUC	∼
	Beta	↑ Amp in all regions ↑ AUC in all regions			↓ Amp in all regions ↓ AUC in all regions
	Low-gamma	∼			∼
	Mid-gamma	↑↑ Amp ∼ AUC	∼ Amp ∼ AUC	∼ Amp ∼ AUC	∼
	High-gamma	Auditory < Parietal < Frontal
	HFO	∼			↑ Amp ↑ AUC	↑↑ Amp ↑↑ AUC	↑↑↑ Amp ↑↑↑ AUC

For each compound, changes within each region are described as ∼ when no change occurs, ↑ when there is an increase, and ↓ when there is a decrease. The number of arrows indicates the intensity of the change. Details of the statistical analyses can be found in Extended Data Table 2-1.