Table 3

Rod outer segment suction recordings analysis parameters

Idark (pA)SfDA (× 10−3 phot−1 μm2)I1/2 (phot μm−2)Tp (ms)Tint (ms)τrec (ms)N
wild type13 ± 18 ± 189 ± 14215 ± 12941 ± 60273 ± 2414 cells
RhoF45L KI12 ± 110 ± 176 ± 15227 ± 10965 ± 39357 ± 6113 cells
p value0.060.520.550.430.740.22
  • Idark, saturated response amplitude measured at the plateau.

  • SfDA, dark-adapted sensitivity.

  • I1/2, intensity required to produce half of the saturated response.

  • Tp, time to peak of a dim flash response.

  • Tint, integration time of the response.

  • τrec, recovery time constant during response shut off.