Number of rats exhibiting symptoms of sickness behavior following the administration of LPS (1.0âmg/kg)
| Lethargy | Huddling | Piloerection | Ptosis | |
|---|---|---|---|---|
| Hour 1 | 8 | 0 | 8 | 0 |
| Hour 2 | 8 | 8 | 8 | 0 |
| Hour 3 | 8 | 8 | 8 | 8 |
| Hour 4 | 8 | 8 | 8 | 8 |
| Hour 5 | 8 | 8 | 8 | 8 |
| Hour 6 | 8 | 8 | 8 | 8 |
Rats treated with LPS were four STs (3 females) and 4 GTs (1 female). Rats treated with vehicle (nâ=â4 per phenotype) did not exhibit any of these symptoms during any time point.