Table 2

Statistical analysis of behavioral changes after 0, 4, or 8 weeks of UCMS in male and female mice

Two-way ANOVAUCMSSexUCMS × sex
EPM
 Total distanceF(1,59) = 5.741
p = 0.019 (F > M)
F(2,59) = 12.35
p < 0.0001
 Time in open armsF(2,59) = 19.32
p < 0.0001
F(1,59) = 6.477
p = 0.0136 (F > M)
F(2,59) = 4.976
p = 0.010
 Entries in open armsF(2,59) = 15.72
p < 0.0001
F(1,59) = 6.924
p = 0.0108 (F > M)
 Distance in open armsF(2,59) = 16.25
p < 0.0001
F(1,59) = 21.10
p < 0.0001 (F > M)
F(2,59) = 3.665
p = 0.0316
OF
 Total distanceF(2,80) = 3.241
p = 0.0443
 Time in centerF(2,80) = 11.07
p < 0.0001
 Entries in centerF(2,80) = 6.674
p = 0.0021
 Thigmotaxis ratioF(2,80) = 5.261
p = 0.0071
CPA
 Post-pre time in LiCl sideF(2,67) = 3.778
p = 0.0279
F(1,67) = 4.299
p = 0.0420 (F > M)
F(2,67) = 3.479
p = 0.0365
 Marble burying
 No. of marbles buriedF(2,40) = 3.972
p = 0.0267
F(2,40) = 3.948
p = 0.0272
 Splash test
 Time spent groomingF(2,40) = 4.496
p = 0.0177
F(2,40) = 7.946
p = 0.0076 (F > M)
  • F, Female; M, male.