Summary of RS LIV–VI aIC-BLA intrinsic properties
| Groups | RMP (mV) | fAHP (mV) | mAHP (mV) | sAHP (mV) | Input resistance (MΩ) | Sag ratio (%) | Time constant (ms) | AP thresh (mV) | AP Amp (mV) | AP half-width (ms) | Rheobase (pA) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RS LIV–VI aIC-BLA Cage Control | −68.29 ±1.830 (6) | 9.188 ± 1.351 (6) | −2.725 ± 0.6462 (6) | −1.460 ± 0.4409 (6) | 125.7 ± 13.03 (6) | 6.993 ± 3.030 (6) | 15.73 ± 1.333 (6) | −28.44 ± 2.166 (6) | 56.30 ± 1.422 (6) | 0.6950 ± 0.03170 (6) | 115.5 ± 18.62 (6) |
| RS LIV–VI aIC-BLA Water | −69.57 ± 0.9422 (12) | 8.472 ± 0.6792 (12) | −6.144 ± 1.013 (12) | −3.690 ± 0.6876 (12) | 141.5 ±11.75 (12) | 9.735 ± 1.400 (12) | 20.35 ± 2.321 (12) | −32.67 ± 1.561 (12) | 50.79 ± 1.238 (12) | 0.5792 ± 0.01928 (12) | 84.17 ± 19.48 (12) |
| RS LIV–VI aIC-BLA Saccharin 1x | −71.57 ± 1.120 (3) | 3.840 ± 2.530 (3) | −3.210 ± 0.9005 (3) | −2.277 ± 0.7297 (3) | 141.3 ±28.45 (3) | 6.455 ± 3.099 (3) | 17.95 ± 2.856 (3) | −31.86 ± 5.650 (3) | 54.23 ± 2.660 (3) | 0.6167 ± 0.09939 (3) | 134.3 ± 58.52 (3) |
| RS LIV–VI aIC-BLA Quinine 1x | −67.28 ±1.505 (10) | 11.63 ± 1.616 (10) | −5.639 ± 0.8918 (10) | −3.678 ± 0.4895 (10) | 151.4 ± 9.055 (10) | 10.31 ± 1.115 (10) | 23.6 ± 1.77(10) | −30.1 ± 2.732 (10) | 55.53 ± 1.845 (10) | 0.6230 ± 0.0535 (10) | 79.20 ± 12.73 (10) |
| RS LIV–VI aIC-BLA Saccharin 5x | −65.70 ± 2.378 (8) | 4.235 ± 1.141 (8) | −2.530 ± 0.7960 (8) | −1.553 ±0.4915 (8) | 130.1 ± 16.85 (8) | 6.237 ± 1.910 (8) | 17.54 ± 2.561 (8) | −35.50 ± 2.302 (8) | 54.09 ± 1.734 (8) | 0.5788 ± 0.05034 (8) | 81.13 ±15.88 (8) |
| RS LIV–VI aIC-BLA Saccharin 1x (4 h) | −70.17 ± 0.9075 (11) | 7.383 ± 1.439 (11) | −3.165 ± 0.9897 (11) | −2.359 ± 0.6647 (11) | 153.3 ± 12.96 (11) | 8.782 ± 1.389 (11) | 26.28 ± 2.596 (11) | −28.43 ± 1.652 (11) | 51.66 ± 3.053 (11) | 0.7773 ± 0.04702 (11) | 88.73 ± 12.25 (11) |
| RS LIV–VI aIC-BLA Saccharin 2x | −69.79 ± 1.921 (7) | 7.180 ± 1.402 (7) | −5.016 ± 1.460 (7) | −3.581 ± 0.6324 (7) | 182.6 ± 19.62 (7) | 9.297 ± 2.347 (7) | 18.36 ± 2.842 (7) | −30.36 ± 1.638 (7) | 54.62 ± 2.058 (7) | 0.6614 ± 0.04149 (7) | 54.86 ± 8.207 (7) |
| RS LIV–VI aIC-BLA CTA Retrieval | −69.9 ± 1.116 (15) | 9.967 ± 1.216 (15) | −5.667 ± 0.6647 (15) | −3.297 ± 0.3599(15) | 156.7 ± 10.11 (15) | 10.71 ± 1.536 (15) | 24.08 ± 2.023 (15) | −33.9 ± 1.132 (15) | 54.89 ± 1.13 (15) | 0.5633 ± 0.01703 (15) * | 91.8 ± 31.15 (15) |
| RS LIV–VI aIC-BLA Extinction | −60.93 ± 3.263 (3) | 7.620 ± 1.907 (3) | −6.027 ± 1.062 (3) | −5.797 ± 1.997 (3) | 224.2 ± 21.29 (3) | 7.515 ± 2.666 (3) | 28.69 ± 2.138 (3) | −31.1 ± 1.372 (3) | 46.98 ± 4.432 (3) | 0.8233 ± 0.02603 (3) | 36.67 ± 13.33 (3) |
| RS LIV–VI aIC-BLA Reinstatement | −67.95 ± 1.725 (5) | 4.932 ± 1.893 (5) | −6.532 ± 0.3344 (5) | −3.228 ± 0.3214 (5) | 221.2 ± 18.9 (5) | 9.486 ± 1.846 (5) | 22.58 ± 2.632 (5) | −33.31 ± 2.035 (5) | 44.58 ± 4.569 (5) | 0.918 ± 0.203 (5) | 55 ± 6.885 (5) |
Values are expressed in mean ± SEM. The number of cells is in parentheses. Statistical analysis was performed by One-way ANOVA post hoc Tukey’s and Dunn’s multiple comparisons. Student’s t test was performed for the comparison of two groups. RMP, resting membrane potential; fAHP, mAHP, and sAHP, fast, medium, and slow after hyperpolarization potentials, respectively; AP Thresh, action potential threshold; AP Amp, action potential amplitude; AP half-width, action potential half-width.
*RS LV/VI aIC-BLA Saccharin 1x vs. CTA Retrieval, *p < 0.05.