Table 1

Fold change ratios of microglial CD68 and Iba-1 expression in the control region (dorsomedial border of ipsilateral retinal terminals) of Ten-m3 knock-out and wild-type mice dLGNs show no changes and are all centered around a value of 1

		Fold change ratio (DM ROI/dlGN)
		Iba-1 “avg size”	Iba-1 “% area”	CD68 “avg size”	CD68 “% area”
SE-WT	Mean	0.98	1.15	0.98	1.07
SE-WT	SD	0.14	0.14	0.17	0.15
EE-WT	Mean	0.94	1.19	0.94	1.03
EE-WT	SD	0.09	0.25	0.09	0.27
SE-KO	Mean	0.99	0.94	1.00	1.29
SE-KO	SD	0.12	0.20	0.39	0.49
EE-KO	Mean	0.96	1.03	0.98	1.02
EE-KO	SD	0.08	0.28	0.22	0.35

Low-power images of Iba-1 and CD68 expression in the dLGNs of 3.5-week-old wild-type (WT, 4 animals per housing condition) and Ten-m3 knock-out (KO, 5 animals per housing condition) mice underwent image binarization as depicted in Figure 6, and values for average size and % area extracted for the whole dLGN and specific dorsomedial (D-M) ROI (dorsomedial border of ipsilateral retinal terminals in the dLGN). Fold change ratios (ROI/dlGN) were determined for each section. Presented are group means and associated standard deviation (SD). Dorsomedial (DM); standard enrichment (SE); environmental enrichment (EE).