Validating spike detector results
| Patient | Spiking sites | Detector highest 5% electrodes | Percentage |
|---|---|---|---|
| 1 | RAH1-3, RA1-3, REC1-3, RPHG1-3, LA1-3 | RAH1, RAH 2, REC 1 | 100% |
| 4 | RA1-3, REC1-3, RAH1-3, RPHG1-3, LA1-3, LEC1-3, LAH1-3, LPHG1-3 | RA1, RA2, LAH2, LAH3, LAH1 | 100% |
| 5 | RAH1-3, RA1-3, RPH1-3, LAH1-3, REC1-3 | RPH3, RAH3, RA2, ROF3 | 75% |
| 7 | RA5-6, REC5-6, RAH1-6, RPHG3-6, RSTGP2-3, RMC1-4, LAH1-2 | RA2, RAH1, RAH2, RPHG6, RPSTG2, REC2, RAH5 | 70% |
| 8 | LA3-4, LAH1-2, LEC1-4, RA1-2, RAH1-2 | RAH1, LEC1, REC1, REC2, RAH2 | 60% |
| 11 | LAH1-3, LA1-3, LEC1-3, RAH1-3, RA1 3, REC1-3 | RA7, REC3, LEC 1, REC1, LAH3 | 80% |
| 14 | LEC1-3, LMH1-3 | LEC1, LEC2, LMH1, LA1 | 75% |
| 15 | REC4-5, RMH1-2, LEC1-2, LMH1-2 | REC5, LEC3, RMH1 | 66% |
| 16 | RA1-7, RAH1-4, REC1-7, RPHG4-7, ROF3-7, LA1-7, LEC1-7, LAH1-7, LPHG1-7 | REC1, REC2, LA2 | 100% |
| 17 | RSTA2-3, RSTP3-4 | RSTA3, RMH1, RSTP3, RIPP8, LST5 | 40% |
| 18 | REC1-4, RMH1-3, LA1-2, LEC1-2, LMH1-2 | REC1, REC2, RMH2, RA2 | 75% |
| 19 | REC4-7, RMH4-7, RPH4-7, RSTG1-7 | RA2, RMH5, RA1, RMH4 | 50% |
| 20 | RA1-2, REC1-2, RMH1-2, RPHG1-2, LA1-2, LEC1-2, LMH1-2, LPHG1-2, | REC1, RMH3, LMH1, LEC2 | 80% |
| 21 | RA1-2, RMH1-2, LEC1-3, LMH1-2, LA1-2 | RA4, RMH5, LEC1, LA1 | 50% |
| 22 | LEC1-3, LA1-3, LEC4-7, LA4-7 | LEC,1, LA1, RA1, RAH1 | 50% |
| 23 | RA1-3, REC1-3, RMH1-3, LA1-3, LEC1-3, LMH1-3 | LEC1, REC4, LMH4, RMH7 | 25% |
| 24 | REC1-4, RMH1-2, RA1-3 | RA1, RA2, LAH1, LA1, LAH2 | 40% |
| 25 | RTO5-7, RMH1-3, LA6-7, LPH5-6 | RMH2, LPH4, LPH5, LPH6 | 75% |
| 26 | LAH1-3, LEC1-2, RMH1-2, RPHG1-3, REC1-3 | LAH1, LAH2, LAH3 | 100% |
| 27 | REC1-3, RMH1-2, RPHG1-2, LMH1-2 | RMH2, RMH4, RPHG2, LMH1 | 75% |
| 28 | LMH4-7, LEC4-7, LA4-7, LPSM4-7, LOF4-7, LAC4-7, REC4-7, RMH4-7, RA4-7 | LMH4, LMH6, LPSM5, LMH5 | 100% |
| 29 | RAH1-3, RA1-3, REC1-3, RPHG1-3 | LEC7, LEC6, REC3, REC2, REC1 | 60% |
| 30 | RA1-2, REC1-2, RMH1-2, RPHG1-2, LA1-2, LEC1-2, LMH1-2, LPHG1-2 | RA1, LMH1, RA2, REC1 | 100% |
| 31 | RA1-7, REC1-7, RAH1-7, RPHG1-7, ROF1-3, RAF1-3, RAC5-7 | RAH1, REC1, REC2, RPHG1, RAH2 | 100% |
| 32 | LEC1-3, LMH1-2, RAH1-7, REC1-7, RPHG1-7 | LEC1, LEC3, REC7, RPHG7 | 100% |
| 33 | REC1-3, RAH1-3, RPHG1-3, LAH1-2, LPHGA1-2, RPHG7-8, LPHGA7-8 | REC1, REC2, RAH1, RPHG3 | 100% |
| 34 | LPH1-2, LEC1-2, LA1-2 | LEC1, LPHG7, LEC2, LPH1 | 75% |
| 35 | LAH1-2, LEC 1-2, LA 1-4, LPHG1-3 | LA3, RA3, LA2 | 66% |
| 36 | LMH1-2, LPHG1-3, LA1-2, ROF4-5 | LPHG1, LPHG2, LA1 | 100% |
| 37 | LEC1-2, LAH1-2, REC1-2, RAH1-2 | LA1, LA2, LAH1, LA7 | 25% |
| 38 | RSTG1-4, RPT 7-8, LPT1-2, LSTG5-7, LEC5-7, LAH5-7, LMTG3-7, REC3-7 | LAH6, LAH5, RAH6, RPHG6 | 50% |
| 39 | REC1-3, RMH1-3, RMNH3-7, RPNH2-6, RINH4-6, LPC 5-8 | RMH1, LPC7, RMH3, RMNH5 | 100% |
| 40 | LEC1-4, LA1-4, LA5-7, LAH1-4, LPNH6-8, LSTG1-5 | LEC1, LEC2, LA1, LEC3 | 100% |
| 41 | RSTGA1-4, RSTG1-4, LSTG1-4 | LSTG2, RPST4, LSTG1, LSTG3 | 75% |
| 42 | REC1-7, RSTA1-7, RSTG1-7, RMH1-7, RIF1-7, RSO3-7, RIO3-7, RAIP3-7 | RIO1, RSTG4, RAIP7, RMH6, RSTG3 | 80% |
| 43 | LEC1-3, LA1-3, RA1-3, REC1-3, LOF3-7, ROF3-7 | LA5, LOF3, RA3, RA2, LEC1 | 80% |
Twelve patients showed 100% correspondence in the top 5% of channels with the highest spike rates between the automated spike detector and those manually identified channels containing interictal discharges. Twenty patients showed at least 50%, 11 of which with >70% correspondence. Only four patients <40% correspondence.
R: right, L: left, TP = temporal pole, FP = frontal pole, A = amygdala, OF = orbitofrontal, EC = entorhinal cortex, F = frontal lobe, AH = anterior hippocampus, FO = frontal operculum, MH = middle hippocampus, AC = anterior cingulate, PH = posterior hippocampus, MC = middle cingulate, PHG = parahippocampal gyrus, PC = posterior cingulate, FG = fusiform gyrus, SMA = supplementary motor area, PT = posterior temporal, STG = superior temporal gyrus, AP = anterior parietal lobe, O = occipital lobe, OT = occipital-temporal border.