Table 2

Descriptive statistics and statistical parameters from two-way ANOVA for recording quality parameters and passive properties (Fig. 2)

Descriptive statistics (mean ± SEM)
Property	3-week controls	3-week PNA	Adult controls	Adult PNA
Series resistance (MΩ)	12.2 ± 0.8	12.259 ± 0.8	13.0 ± 0.8	12.841 ± 0.729
Capacitance (pF)	11.9 ± 0.9	11.8 ± 0.6	12.5 ± 0.9	13.654 ± 0.651
Input resistance (MΩ)	648.6 ± 30.2	710.3 ± 39.3	858.6 ± 53.4	775.946 ± 41.81
Holding current (pA)	−63.9 ± 5.8	−61.6 ± 4.6	−48.2 ± 5.3	−48.456 ± 3.820

Two-way ANOVA
Property	Age	Treatment		Interaction
Series resistance (MΩ)	Diff, −0.7058 [Cl, −2.250, 0.8387] F_(1,60) = 0.8356; p = 0.3643	Diff, 0.04112 [Cl, −1.503, 1.586] F_(1,60) = 0.002837; p = 0.9577		Diff, −0.2489 [Cl, −2.840, 3.338] F_(1,60) = 0.02597; p = 0.8725
Capacitance (pF)	Diff, −1.220 [Cl, −2.750, 0.3089] F_(1,60) = 2.548; p = 0.3906	Diff, −0.5158, [Cl, −2.045, 1.014] F_(1,60) = 0.4551; p = 0.5025		Diff, 1.322 [Cl, −4.381, 1.736] F_(1,60) = 0.7478; p = 0.5025
Input resistance (MΩ)	Diff, −137.8 [Cl, −221.8, −53.87] F_(1,60) = 10.78; p = 0.0017	Diff, 10.43 [Cl, −73.53, 94.39] F_(1,60) = 0.06174, p = 0.8046		Diff, −144.4 [Cl, −312.3, 23.56] F_(1,60) = 2.957; p = 0.0907
	Bonferroni	3-week VEH vs 3-week PNA	3-week VEH vs adult VEH	3-week PNA vs adult PNA	Adult VEH vs adult PNA
		p > 0.9999	p = 0.0065	p ≥ 0.9999	p > 0.9999
Holding current (pA)	Diff, −14.42 [Cl, −24.17, −4.658] F_(1,60) = 8.732; p = 0.0045	Diff, −0.9966 [Cl, −10.75, 8.761] F_(1,60) = 0.04174; p = 0.8388		Diff, −2.608 [Cl, −22.12, 16.91] F_(1,60) = 0.07146; p = 0.7901
	Bonferroni	3-week VEH vs 3-week PNA	3-week VEH vs adult VEH	3-week PNA vs adult PNA	Adult VEH vs adult PNA
		p > 0.9999	p = 0.1846	p = 0.3271	p > 0.9999

Bold indicates p < 0.05.