Two-way ANOVA parameters for action potential properties (Fig. 3)
| Property | Age | Treatment | Interaction | ||
|---|---|---|---|---|---|
| Threshold (mV) | Diff, 1.170 [Cl, −3.918, 0.7768] F(1,52) = 1.803; p = 0.1852 | Diff, 0.9859 [Cl, −1.361, 3.333] F(1,52) = 0.7103; p = 0.4032 | Diff, −0.01028 [Cl, −4.705, 4.684] F(1,52) = 1.932e-005; p = 0.9965 | ||
| Latency (s) | Diff, −0.05101 [Cl, −0.1089, 0.006901] F(1,51) = 0.3.127; p = 0.0.0830 | Diff, 0.003030 [Cl, −0.05489, 0.06095] F(1,51) = 0.0.01103; p = 0.9168 | Diff, −0.05693 [Cl, −0.1728, 0.05890] F(1,51) = 0.9735; p = 0.3285 | ||
| Amplitude (mV) | Diff, 1.731 [Cl, −0.5921, 4.055] F(1,51) = 2.238; p = 0.1408 | Diff, −0.9231 [Cl, −3.247, 1.400] F(1,51) = 0.0.6361; p = 0.4288 | Diff, 0.002851 [Cl, −4.650,4.644] F(1,51) = 1.517e006; p = 0.9990 | ||
| FWHM (ms) | Diff, 0.02731 [Cl, −0.03989, 0.09454] F(1,51) = 0.6660; p = 0.4183 | Diff, −0.01879 [Cl, −0.8601, 0.04843] F(1,51) = 0.3149; p = 0.5771 | Diff, 0.05826 [Cl, −0.07618, 0.1927] F(1,51) = 0.7568; p = 0.3884 | ||
| Rate of rise (mV/ms) | Diff, −0.01261 [Cl, −0.04178, 0.01657] F(1,51) = 0.7524; p = 0.3898 | Diff, 0.01453 [Cl, −0.04740, 0.01095] F(1,51) = 0.2155; p = 0.2155 | Diff, −0.0002991 [Cl, −0.05865, 0.05805] F(1,51) = 0.0001059; p = 0.9918 | ||
| Rheobase (pA) | Diff, 4.479 [Cl, 0.5934, 8.365] F(1,51) = 5.355; p = 0.0247 | Diff, 1.146 [Cl, −2.740, 5.032] F(1,51) = 0.3505; p = 0.5565 | Diff, 2.708 [Cl, −5.063, 10.48] F(1,51) = 0.4895; p = 0.4873 | ||
| Bonferroni | 3-week VEH vs 3-week PNA | 3-week VEH vs adult VEH | 3-week PNA vs adult PNA | Adult VEH vs adult PNA | |
| p > 0.9999 | p = 0.2568 | p > 0.9999 | p > 0.9999 | ||
| AHP amplitude (mV) | Diff, 1.827 [Cl, −0.01161, 3.666] F(1,51) = 3.980; p = 0.0514 | Diff, 1.369 [Cl, −0.4701, 3.208] F(1,51) = 2.233; p = 0.1412 | Diff, 0.7832 [Cl, −2.895, 4.461] F(1,51) = 0.1827; p = 0.6708 | ||
| Bonferroni | 3-week VEH vs 3-week PNA | 3-week VEH vs adult VEH | 3-week PNA vs adult PNA | Adult VEH vs adult PNA | |
| p > 0.9999 | p = 0.6064 | p > 0.9999 | p > 0.9999 | ||
| AHP time (ms) | Diff, −0.7990 [Cl, −1.538, −0.05992] F(1,51) = 4.710; p = 0.0347 | Diff, −0.3644 [Cl, −1.103, 0.3747] F(1,51) = 0.9797; p = 0.3270 | Diff, −0.1663 [Cl, −1.644, 1.312] F(1,51) = 0.05100; p = 0.8222 | ||
| Bonferroni | 3-week VEH vs 3-week PNA | 3-week VEH vs adult VEH | 3-week PNA vs adult PNA | Adult VEH vs adult PNA | |
| p > 0.9999 | p = 0.6283 | p = 0.9836 | p > 0.9999 | ||
Bold indicates p < 0.05.