Results from statistical analyses
| Distribution (Shapiro–Wilk test) | Statistical test | 95% CI | |
|---|---|---|---|
| a | Max # of action potentials AIR: (W = 0.9109, p = 0.2501) CIE: (W = 0.8702, p = 0.0779) | Repeated-measures mixed effects analysis (AIR n = 11 cells) (CIE n = 11 cells) | [−9.179, 4.229] |
| b | AIR: (W = 0.8999, p = 0.1841) CIE: (W = 0.9601, p = 0.7728) | Unpaired t test (AIR n = 11 cells) (CIE n = 11 cells) | [0.95, 13.92] |
| c | AIR: (W = 0.9038, p = 0.2414) CIE: (W = 0.9219, p = 0.4082) | Unpaired t test (AIR n = 10 cells) (CIE n = 9 cells) | [−2.03, 21.82] |
| d | AIR: (W = 0.9507, p = 0.6765) CIE: (W = 0.9238, p = 0.4244) | Unpaired t test (AIR n = 10 cells) (CIE n = 9 cells) | [−0.66, 0.07] |
| e | Max # of action potentials AIR: (W = 0.8757, p = 0.0624) CIE: (W = 0.9375, p = 0.3874) | Repeated-measures mixed effects analysis (AIR n = 13 cells) (CIE n = 14 cells) | [−11.46, 5.557] |
| f | AIR: (W = 0.9477, p = 0.5636) CIE: (W = 0.9747, p = 0.9327) | Unpaired t test (AIR n = 13 cells) (CIE n = 14 cells) | [0.09, 13.92] |
| g | AIR: (W = 0.9762, p = 0.9635) CIE: (W = 0.9140, p = 0.2404) | Unpaired t test (AIR n = 12 cells) (CIE n = 12 cells) | [−10.23, 12.55] |
| h | AIR: (W = 0.9780, p = 0.9744) CIE: (W = 0.9127, p = 0.2309) | Unpaired t test (AIR n = 12 cells) (CIE n = 12 cells) | [−0.419, 0.538] |
| i | AIR: (W = 0.9214, p = 0.4575) CIE: (W = 0.8161, p = 0.1535) | Repeated-measures mixed effects ananlysis (AIR n = 20 cells) (CIE n = 11 cells) | [−0.09, 0.31] |
| j | AIR Physo: (W = 0.9475, p = 0.2814) CIE Physo: (W = 0.9516, p = 0.3920) AIR Opto: (W = 0.9906, p = 0.9988) CIE Opto: (W = 0.8977, p = 0.1730) | Two-way ANOVA Physostigmine (AIR n = 22 cells) (CIE n = 20 cells) Opto (AIR n = 20 cells) (CIE n = 11 cells) | [−25.95, −10.85] |
| k | AIR: (W = 0.9901, p = 0.9802) CIE: (W = 0.7989, p = 0.0793) | Repeated-measures mixed effects analysis (AIR n = 12 cells) (CIE n = 14 cells) | [−0.1439, 0.3015] |
| l | Baseline: (W = 0.9039, p = 0.4509) TTX: (W = 0.8826, p = 0.3498) 4-AP: (W = 0.9148, p = 0.5084) | Repeated-measures one-way ANOVA (AIR n = 4 cells) | Baseline vs TTX [789, 2301] Baseline vs 4-AP [−681.5, 830.2] |
| m | AIR: (W = 0.9564, p = 0.7315) CIE: (W = 0.9714, p = 0.9086) | Unpaired t test (AIR n = 12 cells) (CIE n = 8 cells) | [−0.5509, 0.7032] |
| n | AIR: (W = 0.9634, p = 0.8135) CIE: (W = 0.9061, p = 0.3274) | Repeated-measures mixed effects analysis (AIR n = 12 cells) (CIE n = 8 cells) | [4.821, 953.1] |
| o | Baseline: (W = 0.8142, p = 0.1053) TTX: (W = 0.9942, p = 0.9922) 4-AP: (W = 0.8697, p = 0.2652) | Repeated-measures one-way ANOVA (AIR n = 5 cells) | Baseline vs TTX [−63.72, −0.17] Baseline vs 4-AP [−36.29, 27.27] |
| p | AIR: (W = 0.9542, p = 0.3814) CIE: (W = 0.9417, p = 0.2578) | Unpaired t test (AIR n = 22 cells) (CIE n = 20 cells) | [−0.64, 1.16] |
| q | AIR: (W = 0.9664, p = 0.6481) CIE: (W = 0.9918, p = 0.8271) | Repeated-measures mixed effects ANOVA (AIR n = 6 cells) (CIE n = 5 cells) | [5.037, 44.60] |
| r | AIR: (W = 0.901, p = 0.3796) CIE: (W = 0.9130, p = 0.4566) | Repeated-measures mixed-effects analysis (AIR n = 22 cells) (CIE n = 20 cells) | [−0.07, 24.86] |
| s | AIR: (W = 0.8641, p = 0.9306) CIE: (W = 0.9306, p = 0.5559) | Unpaired t test (AIR n = 9 cells) (CIE n = 7 cells) | [−69.07, 37.75] |
| t | AIR (W = 0.9504, p = 0.5666) CIE: (W = 0.9391, p = 0.5433) | Repeated-measures two-way ANOVA (AIR n = 7) (CIE n = 5) | [−4.37, 0.35] |
| u | AIR (W = 0.9998, p = 0.9711) CIE: (W = 0.7962, p = 0.1056) | Repeated-measures two-way ANOVA (AIR n = 9) (CIE n = 6) | [−0.8789, 0.005] |