Membrane properties of CA1 pyramidal neurons across day and night
| Day | Night | ||
|---|---|---|---|
| Mean ± SEM (n, N) | Mean ± SEM (n, N) | ||
| Baseline (mV) | Anterior | −70.57 ± 0.84 (33,11) | −69.79 ± 0.78 (33,14) |
| Posteriora | −69.99 ± 0.94 (27,11) | −67.53 ± 0.82 (31,11) | |
| Input resistance (MΩ) | Anterior | 63.73 ± 2.84 (33,11) | 64.81 ± 2.71 (33,14) |
| Posterior | 73.3 ± 3.43 (27,11) | 78.16 ± 3.53 (31,11) | |
| Sag amplitude (mV) | Anterior | 4.84 ± 0.36 (33,11) | 4.94 ± 0.33 (33,14) |
| Posterior | 5.63 ± 0.47 (27,11) | 6.43 ± 0.41 (31,11) | |
| AP response slope | Anterior | 0.053 ± 0.004 (33,11) | 0.051 ± 0.005 (33,14) |
| Posterior | 0.052 ± 0.005 (27,11) | 0.046 ± 0.01 (31,11) | |
| Max (Hz) | Anterior | 16.58 ± 0.96 (33,11) | 18.27 ± 0.84 (33,14) |
| Posterior | 18.37 ± 1.06 (27,11) | 19.42 ± 0.818 (31,11) | |
| Imax (pA) | Anterior | 418.18 ± 13.96 (33,11) | 416.36 ± 12.45 (33,14) |
| Posterior | 394.07 ± 15.54 (27,11) | 380.65 ± 15.120 (31,11) | |
| Single action potential properties | |||
| Anterior | Rheobase (pA) | 153.28 ± 10.67 (29,11) | 139.35 ± 10.51 (26,11) |
| Amplitude (mV) | 91.82 ± 0.80 (29,11) | 93.52 ± 0.76 (26,11) | |
| Threshold (mV) | −43.37 ± 0.66 (29,11) | −43.45 ± 0.59 (26,11) | |
| Rise time (ms)b | 0.29 ± 0.01 (29,11) | 0.28 ± 0.01 (26,11) | |
| Male: 0.30 ± 0.01 (28,11) | |||
| Female: 0.28 ± 0.01 (27,11) | |||
| Decay time (ms) | 0.93 ± 0.02 (29,11) | 0.92 ± 0.02 (26,11) | |
| Half-width (ms) | 0.93 ± 0.02 (29,11) | 0.94 ± 0.01 (26,11) | |
| fAHP (mV) | −6.42 ± 0.49 (29,11) | −6.24 ± 0.48 (26,11) | |
| mAHP (mV) | −9.68 ± 0.51 (29,11) | −8.98 ± 0.49 (26,11) | |
| Peak rise (ΔmV/Δms) | 400.25 ± 11.60 (29,11) | 414.86 ± 10.03 (26,11) | |
| Peak fall (ΔmV/Δms) | −98.34 ± 1.98 (29,11) | −99.48 ± 1.62 (26,11) | |
| Posterior | Rheobase (pA) | 120.56 ± 8.75 (27,11) | 120.56 ± 8.75 (27,11) |
| Amplitude (mV) | 91.45 ± 0.81 (27,11) | 91.45 ± 0.81 (27,11) | |
| Threshold (mV) | −42.58 ± 0.59 (27,11) | −42.58 ± 0.59 (27,11) | |
| Rise time (ms) | 0.32 ± 0.01 (27,11) | 0.32 ± 0.01 (27,11) | |
| Decay time (ms) | 1.14 ± 0.03 (27,11) | 1.14 ± 0.03 (27,11) | |
| Half-width (ms) | 1.11 ± 0.03 (27,11) | 1.11 ± 0.03 (27,11) | |
| fAHP (mV) | −5.01 ± 0.43 (27,11) | −5.01 ± 0.43 (27,11) | |
| mAHP (mV) | −8.25 ± 0.41 (27,11) | −8.25 ± 0.41 (27,11) | |
| Peak rise (ΔmV/Δms) | 352.36 ± 10.63 (27,11) | 352.36 ± 10.63 (27,11) | |
| Peak fall (ΔmV/Δms) | −80.31 ± 2.70 (27,11) | −80.31 ± 2.70 (27,11) | |