Table 1

Clusters showing significant differences between deprived Romanian adoptees and nondeprived United Kingdom adoptees in local white matter volumes (all pFWE < 0.05)

Cluster indexCluster size (mm3)Hemi-sphereT valueMax voxel MNI
coordinates (mm)
Annotation
xyz
Nondeprived > deprived
 112,460L6.43−12−23−29Brain stem
6.28−33−17−5IFOF
5.91−33−241IFOF
5.88−33−25−1IFOF
5.48−23−17−6ILF
 24760R4.5833−221IFOF
4.5333−22−1IFOF
4.4326−339IFOF
4.2829−261ILF
 31791L4.56−7−4717Cingulum
4.49−12−4128Cingulum
 4398L4.14−34−706ILF
 5280L4.21−9−8221ILF
 6217L4.1−41−23−13ILF
 7140L4.78−11−6747ILF
 8117L3.8−12−5751Cingulum
 998L3.37−39−3733SLF
 1097L3.86−43−35−7ILF
 1159L3.86−31−6013ILF
 127L3.49−37−27−16ILF
Deprived > nondeprived
 182L6.00−32−4−16Uncinate
Deprivation duration
No significant clusters
Subnutrition
No significant clusters
  • L, left; R, right; IFOF, inferior fronto-occipital fasciculus; ILF, inferior longitudinal fasciculus. Threshold-free cluster enhancement (TFCE) was applied and all analyses were controlled for family-wise error rate (FWE).