Table 4

ANOVA results of Western blots of frontal cortex

ProteinInteractionMain effectF(df,error) valuep value
pAKT Ser473Treatment × GenotypeF(1,19) = 0.1060.749
TreatmentF(1,19) = 0.0300.865
GenotypeF(1,19) = 0.3780.546
pAKT Thr308Treatment × GenotypeF(1,19) = 0.8510.368
TreatmentF(1,19) = 0.1090.745
GenotypeF(1,19) = 0.0120.913
pAMPKTreatment × GenotypeF(1,19) = 0.7650.393
TreatmentF(1,19) = 5.1660.035*
GenotypeF(1,19) = 1.1150.304
pCREBTreatment × GenotypeF(1,19) = 0.0430.838
TreatmentF(1,19) = 2.6550.120
GenotypeF(1,19) = 0.0330.859
peIF2αTreatment × GenotypeF(1,19) = 0.2350.634
TreatmentF(1,19) = 0.3700.550
GenotypeF(1,19) = 0.2650.613
pERKTreatment × Genotype × BandF(1,19) = 1.1740.292
Treatment × BandF(1,19) = 0.5600.464
Genotype × BandF(1,19) = 0.3030.588
Treatment × GenotypeF(1,19) = 2.0990.164
TreatmentF(1,19) = 0.3500.561
GenotypeF(1,19) = 0.4020.533
BandF(1,19) = 145.346<0.001*
pGSK3α/βTreatment × Genotype × BandF(1,19) = 0.9710.337
Treatment × BandF(1,19) = 1.7580.201
Genotype × BandF(1,19) = 0.0130.911
Treatment × GenotypeF(1,19) = 0.2400.630
TreatmentF(1,19) = 0.5680.460
GenotypeF(1,19) = 0.0040.953
BandF(1,19) = 260.590<0.001*
pmTORTreatment × GenotypeF(1,19) = 0.0520.822
TreatmentF(1,19) = 0.0340.856
GenotypeF(1,19) = 0.0460.832
p-p70 S6K Thr389Treatment × Genotype × BandF(1,19) = 2.2920.146
Treatment × BandF(1,19) = 4.4510.048*
Genotype × BandF(1,19) = 0.0010.975
Treatment × GenotypeF(1,19) = 0.8820.359
TreatmentF(1,19) = 0.0900.767
GenotypeF(1,19) = 1.2280.282
BandF(1,19) = 180.660<0.001*
p-p70 S6K Thr421/Ser424Treatment × Genotype × BandF(1,19) = 0.0850.773
Treatment × BandF(1,19) = 0.0030.957
Genotype × BandF(1,19) = 0.2790.603
Treatment × GenotypeF(1,19) = 0.2650.613
TreatmentF(1,19) = 0.5350.473
GenotypeF(1,19) = 0.1500.702
BandF(1,19) = 30.355<0.001*
pS6Treatment × Genotype × SiteF(1,19) < 0.0010.985
Treatment × SiteF(1,19) < 0.0010.993
Genotype × SiteF(1,19) = 0.0490.826
Treatment × GenotypeF(1,19) = 0.9470.343
TreatmentF(1,19) = 0.8130.378
GenotypeF(1,19) = 6.2160.022*
SiteF(1,19) = 6.6340.019*
  • * Denotes statistical significance p ≤ 0.05.