Table 5

ANOVA results strain differences in physiological variables

Variable	Interaction	Main effect	F_(df,error) value	p value
Body weight	Strain × Genotype		F_(1,30) = 0.013	0.911
		Strain	F_(1,30) = 103.935	<0.001*
		Genotype	F_(1,30) < 0.001	0.990
Arterial blood pressure	Strain × Genotype		F_(1,30) = 0.001	0.981
		Strain	F_(1,30) = 2.300	0.140
		Genotype	F_(1,30) = 0.065	0.801
Arterial blood glucose concentration	Strain × Genotype		F_(1,30) = 0.065	0.801
		Strain	F_(1,30) < 0.001	0.983
		Genotype	F_(1,30) = 0.0.439	0.513
Arterial plasma leucine concentration	Strain × Genotype		F_(1,30) = 0.428	0.518
		Strain	F_(1,30) = 14.494	<0.001*
		Genotype	F_(1,30) = 2.187	0.150

↵*Denotes statistical significance p ≤ 0.05.
Comparison of physiological variables between the Tsc2^Mjg^+/− mice used in this study (values in Table 1) and Tsc2^Djk^+/− mice used in our previous study (Saré et al., 2018). Mean values in control and Tsc2^Djk^+/− mice, respectively, as follows: body weight: 98 ± 1 and 96 ± 2 g; arterial blood pressure: 109 ± 1 and 109 ± 2 mmHg; arterial blood glucose: 6.5 ± 0.4 and 6.1 ± 0.5 mm; arterial plasma leucine: 116 ± 4 and 111 ± 3 μm.