Table 1

Hub proteins from differential protein and phosphopeptide expression networks in the DMS and DLS of males and females

GeneProteinMCC
DLS hub proteins for global proteome network in males
Copb1Coatomer subunit β-1242
Dynll2Dynein light chain 2, cytoplasmic241
Capza2F-actin-capping protein subunit α-2240
Copb2Coatomer subunit β-2240
Copg1Coatomer subunit γ-1240
DMS hub proteins for global proteome network in males
Btbd1BTB/POZ domain-containing protein 15760
Asb6Ankyrin repeat and SOCS box protein 65760
Kbtbd7Kelch repeat and BTB (POZ) domain containing 75760
Fbxw10F-box/WD repeat-containing protein 105760
Fbxo7F-box only protein 75760
DLS hub proteins for phosphoproteome network in males
Sptbn1Spectrin beta chain, nonerythrocytic 17
Ank2Ankyrin-26
Ank3Ankyrin-36
Ank1Ankyrin-16
Rpl3760S ribosomal protein L376
DLS hub proteins for phosphoproteome network in females
Gapvd1GTPase-activating protein and VPS9 domain-containing protein 16
Reps1RalBP1-associated Eps domain-containing protein 16
Arrb1β-Arrestin-16
Dnm3Dynamin-36
Dlg2Disks large homolog 21
DMS hub proteins for phosphoproteome network in males
Hspa8Heat shock cognate 71 kDa protein4
CaskPeripheral plasma membrane protein CASK3
Epb4.1l1Band 4.1-like protein 13
Epn2Epsin-22
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit β2
DMS hub proteins for phosphoproteome network in females
VclVinculin4
Cyfip1Cytoplasmic FMR1-interacting protein 12
Lrrc7Leucine-rich repeat-containing protein 72
Arhgef2Rho guanine nucleotide exchange factor 21
CaskPeripheral plasma membrane protein CASK1