Table 1

Statistics table

Data structureType of testComparison95% confidence interval
aNormally distributedTwo-way RM ANOVA
Bonferroni post hoc testPEGPH20 vs API buffer day 1368.4–7286
Bonferroni post hoc testPEGPH20 vs API buffer day 267.36–6985
Bonferroni post hoc testPEGPH20 vs API buffer day 3695.6–7613
bNormally distributedTwo-way RM ANOVA
Bonferroni post hoc testPEGPH20 vs vehicle day 511.85–146.1
cNormally distributedTwo-way RM ANOVABonferroni post hoc test−8.005–12.52
dNon-normally distributedKruskal–Wallis testTest does not generate confidence interval
eNon-normally distributedMann–Whitney U test−1.000–3.000
fNon-normally distributedMann–Whitney U test−1.000–2.000
gNon-normally distributedMann–Whitney U test−80.66–89.10
hNon-normally distributedMann–Whitney U test1.700–24.62
iNon-normally distributedMann–Whitney U test−12.70–24.30
jNon-normally distributedMann–Whitney U test1.700–24.62
kNormally distributedχ2 testTest does not generate confidence interval
lNormally distributedUnpaired t test22,155–108,900
mNormally distributedMixed-effects analysisPEGPH20 vs vehicle day 1−7169 to −963.0
Bonferroni post hoc testPEGPH20 vs vehicle day 2−6877 to −456.6
Bonferroni post hoc testPEGPH20 vs vehicle day 3−8772 to −279.7
Bonferroni post hoc testPEGPH20 vs PEGPH20+AP day 4110.9–2674
Bonferroni post hoc testPEGPH20 vs PEGPH20+AP day 5309.0–2507
Bonferroni post hoc testPEGPH20 vs PEGPH20+AP day 6389.1–3866
Bonferroni post hoc testPEGPH20 vs PEGPH20+AP day 7580.0–3549
nNormally distributedOne-way RM ANOVA
Bonferroni post hoc testPEGPH20 vs PEGPH20+AP395.7–2221
Bonferroni post hoc testPEGPH20 vs vehicle−4459 to −2177
Bonferroni post hoc testPEGPH20+AP vs vehicle−5256 to −3997
Bonferroni post hoc testAP vs vehicle1464–4666