Table 12

Features of the transient response of the SNr neurons, same as Table 11; however, by pooling synaptic weights corresponding to Figure 6

Normal (triphasic)PD-biphasicPD-triphasic
Early excitation (EE)
Latency (ms)7.0 ± 0, 6.93 ± 0.507.0 ± 0, 7.0 ± 07.0 ± 0, 7.0 ± 0
Duration (ms)3.0 ± 0, 4.04 ± 0.4323.0 ± 0.79, 21.01 ± 0.083.69 ± 0.46, 4.03 ± 0.18
Deviation of peak amplitude from the baseline (HpHbas )38.02 ± 2.76, 63.30 ± 4.3975.84 ± 12.53, 67.14 ± 1.65153.63 ± 6.43, 159.96 ± 3.67
Early inhibition (EI)*ND
Latency (ms)10.0 ± 0, 11.0 ± 010.69 ± 0.46, 11.03 ± 0.18
Duration (ms)5.56 ± 0.49, 6.0 ± 0.03.66 ± 0.77, 4.96 ± 0.18
Deviation of peak amplitude from the baseline (HpHbas )−29.18 ± 0.54, −29.64 ± 0.44−11.7 ± 1.73, −15.16 ± 0.34
Late excitation (LE)##
Latency (ms)15.56 ± 0.49, 16.94 ± 0.7414.35 ± 0.47, 16.0 ± 0.0
Duration (ms)7.66 ± 0.51, 9.08 ± 0.4914.21 ± 0.71, 12.0 ± 0.0
Deviation of peak amplitude from the baseline (HpHbas )156.72 ± 16.24, 136.91 ± 1.57139.45 ± 2.91, 147.74 ± 1.30
Late inhibition (LI)
Latency (ms)23.22 ± 0.42, 26.03 ± 0.5430.0 ± 0.79, 28.00 ± 0.0828.57 ± 0.49, 28.0 ± 0.0
Duration (ms)13.17 ± 0.96, 10.53 ± 0.8644.09 ± 9.35, 37.24 ± 0.5931.8 ± 1.11, 31.99 ± 0.09
Deviation of peak amplitude from the baseline (HpHbas )−11.81 ± 1.64, −5.11 ± 0.51−16.6 ± 1.72, −20.65 ± 0.30−19.55 ± 1.31, −20.83 ± 0.34
  • Here, the variations in the features in normal state were obtained by simulating the network with the range of synaptic weights of a particular connection between (v - (vv/m)3) and (v + (mvv)3). Similarly, the variations in the features in the PD conditions (PD-biphasic and PD-triphasic) were obtained by simulating the network with the range of synaptic weights of a particular connection between (v + (mvv)3) and (v + 3(mvv)3) (mv, i.e., weight in PD condition). These were done by considering six types of synaptic connections corresponding to Figure 6.