Table 2

Genes that are differentially expressed between NSCs and astrocytes in both the V-SVZ and SGZ (related to Fig. 1, 2)

Astr-enriched genes in V-SVZ + SGZNSC-enriched genes in V-SVZ + SGZ
Gpr37l1Dbi
Sparcl1Sfrp1
Cxcl14*Rpl41
Htra1Rplp0
BcanRps27a
Id2Rpl18a
Aqp4*Rps27
Tril*Rpl35a
Ntsr2Rps19
Atp1b2Rpl13a
Timp4*Rpl9
Car2*Rpl3
Atp1a2Rps14
Eno1Eef1a1
Kcnk1Rpl13
S100b*Rplp1
Dbx2Ptma
Cldn10Rps4x
Btbd17Rpl10
Aplp1Marcksl1
Slc39a12*Rpl23a
Msmo1Rps24
Gja1Rpl17
Slc7a10Rps5
LsampRpl14
Pla2g7Vim
Fjx1Rps9
Gria2Rps23
Plpp3Rps15a
Abhd3*Rps18
F3Rpl37
Gpm6aRpl11
Dclk1Rpl27a
CluRps16
Gjb6*Rps8
Slc4a4*Rpl26
Tmem100Rpl37a
Omg*Rps13
NtmRps10
Eva1aGnas
GrinaRps20
Scg3Rpl32
Arxes2*Rplp2
S1pr1Rpl8
ApoeRps2
Smpdl3aRpl34
Camk2n1Rpl38
mt-Co3Rps21
Acsbg1Rps25
Agpat5Rpl23
Acsl6Rps12
Gpc5Riiad1
Hacd2Rps3a1
Cadm1Rpl7
Fgfr3*Sparc
AldocRpl10a
Hapln1*Rps6
Mfge8Rpl22l1
HbegfRps15
Tuba4aRps28
Hsd11b1*H2afv
Grin2c*Rps7
Tmem176aRps11
Grm3Rtn1
Chst1Fau
Slc38a3Rpl21
Tspan7Rpl31
Macf.1Rpl39
Sepp1Ftl1
Lcat*Rps17
ClmnTmsb4x
Vegfa*Hmgb1
AI464131*Rpl30
Slc6a1Rpsa
Pfkp*Hsp90aa1
Paqr7Ccnd2
Eps8Rpl6
Slc9a3r1Rps3
Tagln3Ascl1
Fermt2Tpt1
mt-Nd1Rpl36a
OafFxyd6
Vcam1Rpl15
Tlcd1Rpl36
Tmem176bFabp7
mt-Atp6Rpl19
mt-CytbRpl4
mt-Nd2Bex4
Cryab*Hmgn1
Serinc1Cd9
Cd81Rpl18
PhyhiplRpl24
Ptprz1Pebp1
Ppp1r3gPsph
Syne1*Rps26
Cd38*Ypel3
MertkCnbp
Appl2Rpl12
Mt1Rpl22
Mfsd2aSwi5
Ank2Zbtb20
Fam20aYbx1
TprkbSptssa
Sept7.Eef2
Pcdh7Tox3
Scrg1Slc38a1
Tmed5Rpl35
Ccdc88aNaca
Ugp2Ywhae
mt-Nd4Plagl1
Cadm2*Rpl29
mt-Co2Sept15.
PtnSmim11
Mt2Arl4c
Pmm1Rpl5
Il18Fbln2
mt-Co1Bex2
2900052N01RikH3f3a
AplnRpl27
Luzp2Mif
Slc6a11Maged1
Slco1c1Marcks
RgccMrfap1
NcanSnrpg
Slc1a3Mfap2
Id3Rpl7a
Acsl3Snrpd2
Phactr3Veph1
Serpine2Tuba1a
P4 ha1Chchd2
Tmem44Ppia
Agt*Tomm7
EnhoJund
Adora2bUbl5
Hacd3Acot1
Tsc22d4H1f0
Cdh10Anapc11
Dhcr7Btf3
Gabrg1*Hdgf
CtsdPfdn5
Cystm1Gnb2l1
Phkg1Trim2
Slc7a11Tead2
Usp53Psip1
Pcdh10Ifitm2
Arhgap5Pdlim4
Sec14l2Ap1s2
NptnRcn1
Thy1Eif3f
Cmtm5Rpl28
Atp13a4Cetn2
Elovl2Clic1
RorbNdn
Fut9Nenf
Sat1Snrpe
Pcdh9Gabarap
Ttyh1Dek
mt-Nd4lPrdx2
PfkmEef1d
Gabrb1Idh2
Fam21Stra13
Cpeb4Sh3bgrl3
Prex1Atpif1
Pmp22Srp9
GatmNsg1
Csrp1Hsbp1
Smpd1Eef1g
Cyp7b1Serf1
Pcdh17Myl9
Tlr3Fam210b
MetrnAif1l
Lgr4Cox7a2l
Chchd10Bex1
Slc14a1Dstn
Rrbp1Tuba1b
Gpr162Rps27l
Abcd2Ap2m1
Gpr37Stmn3
Slitrk2Ahsa1
Elovl5Ptx3
Emc3Trmt112
TnikHmgn2
SarafEef1b2
CntfrCreb5
Aco2Sf3b2
UbcCfdp1
Chst10Tspan13
Plcd4Park7
HmgcrEi24
Tmem229aSec61g
Gstm5Fkbp3
Wscd1Tmem107
Gpi1Tbca
Stt3bSnrpf
HepacamAnp32b
Cd47Atp5e
EdnrbNudc
Mdga2Psmg4
Cyp2j6Pkig
Akt2Sumo2
Pgm2Erh
NeblHcf.c1r1
Olig12810459M11Rik
Mfn1Tmem258
Ddhd1Pfdn2
Trp53bp2Maf1
Rapgef3Bnip3l
CrotAkr1a1
AdkRpa2
Rasa2Rhcg
CkbKif21a
Rnf13Oaz1
Slc20a1Sumo3
Dner2700094K13Rik
Slc27a1H2afy
Irak2St13
mt-Nd3Cetn3
Osbpl1aHbb-bs
Cst3Hint1
Chst2Efnb1
NrcamTubb5
Tpp1Fos
Fgf1Sfr1
Clptm1Eif1ax
Tmem189Nedd8
Capn2Cdc26
Daam2Elof1
NdpHsp90ab1
DmdPtov1
Slc1a4Hnrnpc
HadhbRnaseh2c
Nr1d1Txn1
BaalcRnf187
Psd2Psme1
Aldh1l1Ngfrap1
Hist1 h1cFam32a
Itga6Nop10
Cyp2d22Pbx1
AldoaEif3h
Laptm4bGltscr2
CnpTmpo
Kifc3Efnb3
Pcdh1Aprt
Dnajb9Psme2
Asah1Mettl9
Mfap3lHmgb2
Camk2gRlbp1
CpqSlit2
TankUse1
Gpr146Hsd17b10
PnkdHspe1
MgllPter
Arhgef26Cnpy2
Aifm3Hnrnpf
Slc2a1Btg2
Slc41a1Ywhaq
Fam213aPsenen
Igsf11Bri3
Fgfrl1Wbp5
Adgrl3Gsta4
Etv5Trip6
RP23-4H17.3Mdk
Fut8Mrpl52
Jam2Rac3
Kif1bRan
Usp54Eif3i
Sash1Tma7
Tmbim1G3bp1
VclPax6
Ppp3caNpm1
Pon2Chchd7
Phka1Fkbp4
Chpt1Ccdc80
Mir124-2 hgMbd3
Abi1Hnrnpr
Uqcr10Myl6
Stxbp3Set
Ppp1r1bRanbp1
Prex2Golim4
mt-Nd5Gpx8
Acss2Arl3
Tmx2Bag2
Pid1Ntan1
Tcn2Med28
TfrcDdah2
Dio2Nhp2l1
Trib2Stk11
Slc15a2Gpx1
Itpr2Tsn
Gm2aBasp1
Npas3Msn
Pttg1ipCers4
Acap2Unc119
Insig1Paip2
Csgalnact1Srp14
Mcur1Ift22
Uqcr11Anapc5
S100a13Hnrnpa1
RetsatCnn3
Tmem47Sumo1
Adgrg1Gm8730
 Anp32a
 Tceb2
 Myl12a
 Cacybp
 Emg1
 Ssrp1
 Polr3h
 Nfix
 Puf60
 Ppp1ca
 Rpl23a-ps3
 Romo1
 Cfap20
 Gm17750
 Vgll4
  • Shown are genes that are differentially expressed (FWER < 0.05) between NSCs and astrocytes in both the dentate gyrus and the V-SVZ. Genes identified as differentially expressed by V-SVZ NSCs versus astrocytes in Borrett et al. (2020) were interrogated for their expression in all SGZ NSCs (red cells in Fig. 1B) and all SGZ astrocytes (green and blue cells in Fig. 1B) in the combined dentate gyrus dataset. The left column indicates genes significantly enriched in astrocytes in both the V-SVZ and SGZ, and the right column indicates genes significantly enriched in NSCs in both the V-SVZ and SGZ. Of the astrocyte-enriched genes, 26 (indicated with asterisks in the table) were highly enriched relative to NSCs, and were used to define a shared forebrain niche astrocyte signature as shown in Figures 1G, 2E.