Expression of V-SVZ RP/NSC core identity genes in hippocampal SGZ NSCs and astrocytes (related to Fig. 1)
| Core genes | SGZ NSC abundance (%) | SGZ Astr abundance (%) |
|---|---|---|
| Acaa2 | 21.6 | 17.3 |
| Aldoc | 85.1 | 98.7 |
| Apoe | 90.8 | 99.9 |
| Asrgl1 | 42.9 | 63.4 |
| Ccdc80 | 49.0 | 19.0 |
| Cd63 | 65.6 | 64.2 |
| Ckb | 87.7 | 94.6 |
| Cyr61 | 34.5 | 12.2 |
| Dbi | 99.2 | 92.8 |
| Ddah1 | 72.4 | 59.3 |
| Efhd2 | 40.7 | 36.4 |
| Fabp7 | 94.7 | 75.3 |
| Fgfbp3 | 28.9 | 16.7 |
| Gas1 | 66.9 | 33.9 |
| Gng12 | 51.2 | 53.6 |
| Gpx8 | 30.4 | 12.1 |
| Gsta4 | 29.3 | 11.6 |
| Hes1 | 45.3 | 28.2 |
| Hes5 | 63.6 | 47.9 |
| Hopx | 58.0 | 42.1 |
| Id1 | 34.0 | 26.8 |
| Id3 | 54.6 | 62.0 |
| Id4 | 36.4 | 59.1 |
| Lfng | 32.2 | 26.5 |
| Magt1 | 24.5 | 25.2 |
| Mdk | 72.8 | 43.5 |
| Mfge8 | 78.8 | 82.9 |
| Mlc1 | 51.2 | 79.4 |
| Mt1 | 94.5 | 98.3 |
| Mt2 | 85.6 | 93.3 |
| Mt3 | 94.0 | 99.8 |
| Myo10 | 27.2 | 38.8 |
| Nek6 | 28.4 | 9.2 |
| Nes | 15.4 | 3.5 |
| Nr2e1 | 29.5 | 20.4 |
| Nrarp | 43.3 | 34.8 |
| Oat | 37.6 | 45.2 |
| Pax6 | 55.0 | 32.6 |
| Pdpn | 37.5 | 34.0 |
| Pea15a | 70.8 | 62.3 |
| Phgdh | 66.8 | 53.0 |
| Pon2 | 39.3 | 45.6 |
| Psat1 | 57.3 | 46.0 |
| Ptprz1 | 93.1 | 95.6 |
| Rcn1 | 35.7 | 13.8 |
| Rhoc | 32.0 | 18.3 |
| Serpinh1 | 38.8 | 24.9 |
| Sfrp1 | 33.9 | 6.2 |
| Slc1a3 | 97.5 | 99.6 |
| Slc9a3r1 | 47.3 | 54.2 |
| Sox2 | 59.8 | 65.3 |
| Sox21 | 20.7 | 29.2 |
| Sox9 | 78.2 | 77.1 |
| Sparc | 55.5 | 22.8 |
| Tead2 | 31.3 | 7.0 |
| Tfap2c | 38.6 | 0.7 |
| Tgfb2 | 38.6 | 21.6 |
| Tnc | 50.5 | 29.0 |
| Ttyh1 | 75.0 | 96.5 |
| Vcam1 | 33.2 | 48.3 |
| Veph1 | 24.6 | 1.7 |
| Vim | 66.4 | 18.0 |
| Zfp36l1 | 70.8 | 45.1 |
Shown are 63 of the 79 embryonic cortical signature genes defined in Yuzwa et al. (2017) that are not cell cycle associated and are significantly enriched in SGZ NSCs (cells highlighted in red in Fig. 1B) relative to all other combined cell types in the dentate gyrus from embryogenesis through to adulthood (E16.5–P132; adjusted p value, FWER < 0.05). The relative proportions of SGZ NSCs (red cells in Fig. 1B) and all SGZ astrocytes (green and blue cells in Fig. 1B) that detectably express these mRNAs are also shown.