Table 7

Categorization and expression of the shared adult dormant NSC signature genes in juvenile/adult V-SVZ and SGZ NSCs and astrocytes (related to Fig. 8-10)

	Gene abundance (%)
	V-SVZ populations		SGZ populations
Genes	V-SVZ dNSCs	V-SVZ Astr	SGZ NSCs	SGZ Astr	Category
2310022B05Rik	54.53	48.26	59.91	45.89	Miscellaneous
4930402H24Rik	54.19	54.18	33.02	41.24	Miscellaneous
Acsbg1	63.42	88.50	34.91	69.60	Metabolism (lipid)
Acsl6	60.00	87.46	26.42	69.07	Metabolism (lipid)
Aldoc	98.97	99.48	81.60	99.18	Metabolism
Apoe	99.83	100.00	98.58	100.00	Miscellaneous
Arhgap5	61.20	74.56	55.19	59.63	Signaling
Atp1a2	98.63	99.83	90.09	99.66	Ion + neurotransmitter regulation
Atp1b2	81.20	96.34	74.53	96.90	Ion + neurotransmitter regulation
Bhlhe41	12.14	17.94	21.23	18.83	Gene regulation + RNA binding
Chchd10	75.56	87.98	40.57	81.22	Mitochondrial gene
Clu	98.46	99.83	72.17	99.23	Miscellaneous
Cmtm5	65.30	79.09	47.17	40.17	Signaling
Cpe	100.00	99.30	82.55	98.55	Metabolism
Cspg5	99.49	97.91	59.43	89.74	ECM + adhesion
Csrp1	85.47	91.29	41.04	58.23	Gene regulation + RNA binding
Cst3	100.00	100.00	100.00	99.95	ECM + adhesion
Cxcl14	48.55	93.90	25.47	76.52	Miscellaneous
Dbp	47.18	56.79	28.77	33.54	Gene regulation + RNA binding
Dclk1	85.47	93.73	70.28	83.20	Signaling
Dtna	76.58	65.85	49.06	53.78	ECM + adhesion
Entpd2	38.29	51.92	32.55	19.80	Metabolism
Fam107a	87.18	90.07	31.60	72.99	Miscellaneous
Fxyd1	96.24	86.06	54.72	59.54	Ion + neurotransmitter regulation
Gabrb1	48.38	70.03	53.77	62.68	Ion + neurotransmitter regulation
Gfap	30.43	12.37	49.06	71.10	Miscellaneous
Gja1	92.65	98.43	60.85	99.81	ECM + adhesion
Gm10561	55.56	42.33	49.06	21.06	Miscellaneous
Gm2a	48.89	51.39	39.62	58.52	Miscellaneous
Gm3764	76.41	89.55	83.02	82.58	Miscellaneous
Gnao1	82.91	78.75	56.13	48.50	Signaling
Gpm6a	83.08	96.52	87.74	99.47	Signaling
Gpm6b	98.97	95.82	94.81	97.48	Signaling
Gpr37l1	81.03	99.13	55.66	90.42	Signaling
Gstm1	98.12	96.34	78.30	88.14	Detoxification
Hepacam	75.21	84.84	38.21	62.78	ECM + adhesion
Id4	93.16	93.38	60.38	67.09	Gene regulation + RNA binding
Itih3	26.50	30.49	49.06	23.62	ECM + adhesion
Itm2c	95.21	91.11	55.66	64.86	Miscellaneous
Kcnj10	28.38	22.13	50.47	51.50	Ion + neurotransmitter regulation
Lsamp	67.52	92.51	57.08	74.30	ECM + adhesion
Malat1	100.00	97.39	100.00	99.85	Miscellaneous
Mfge8	94.70	96.52	82.55	80.74	ECM + adhesion
Mgll	54.19	66.20	37.74	61.08	Metabolism (lipid)
Mlc1	91.97	87.63	59.43	79.57	Ion + neurotransmitter regulation
Mmd2	92.48	97.56	81.60	85.24	Signaling
Msi2	84.44	68.64	59.91	41.97	Gene regulation + RNA binding
Mt1	99.32	99.48	98.58	99.95	Detoxification
Mt2	97.78	98.26	94.81	97.97	Detoxification
Mt3	98.97	99.65	99.06	100.00	Detoxification
Neat1	26.67	23.69	34.91	44.68	Miscellaneous
Nrxn1	75.38	81.01	66.04	74.59	ECM + adhesion
Nrxn2	53.16	58.71	47.17	58.18	ECM + adhesion
Ntm	59.49	88.68	45.28	64.86	ECM + adhesion
Ntrk2	96.92	94.60	79.72	94.39	Signaling
Ntsr2	88.38	98.61	59.43	87.85	Signaling
Ogt	76.92	70.91	58.96	41.63	Metabolism
Phkg1	49.06	73.87	21.70	37.46	Signaling
Pitpnc1	56.24	49.13	47.64	36.59	Metabolism (lipid)
Pla2g7	43.76	86.24	33.96	73.23	Metabolism (lipid)
Plpp3	98.29	98.78	92.45	98.69	ECM + adhesion
Prex2	68.89	77.18	60.85	62.00	Signaling
Prnp	98.80	99.13	62.26	79.77	Miscellaneous
Psap	96.41	95.47	74.53	93.47	Miscellaneous
Ptprz1	85.13	93.38	96.70	94.29	Signaling
Qk	76.92	70.56	83.02	92.21	Gene regulation + RNA binding
Ramp1	57.26	75.09	41.98	43.76	Signaling
Riiad1	50.09	11.15	41.98	3.19	Signaling
Rsrp1	95.73	90.77	69.34	70.04	Miscellaneous
S100a1	86.84	80.14	60.85	71.10	Ion + neurotransmitter regulation
S100a16	88.38	88.50	66.51	62.44	Ion + neurotransmitter regulation
S100a6	85.47	46.86	41.04	29.33	Ion + neurotransmitter regulation
S1pr1	73.50	92.16	53.77	89.06	Signaling
Scarb2	30.60	27.00	41.04	36.98	Miscellaneous
Scd2	92.65	78.92	88.68	96.85	Metabolism (lipid)
Scg3	86.32	95.47	50.47	81.99	Miscellaneous
Sdc4	59.66	67.07	45.28	73.86	ECM + adhesion
Selm	66.32	44.60	54.25	42.55	Miscellaneous
Sepp1	80.68	95.64	33.96	84.27	Detoxification
Sfxn5	65.64	58.71	64.15	67.42	Ion + neurotransmitter regulation
Sirpa	60.17	46.34	34.91	47.53	Signaling
Slc1a2	99.32	99.48	96.23	100.00	Ion + neurotransmitter regulation
Slc1a3	98.12	99.13	99.06	99.56	Ion + neurotransmitter regulation
Slc6a1	48.72	74.04	44.81	77.44	Ion + neurotransmitter regulation
Slc6a11	35.21	62.89	47.64	76.86	Ion + neurotransmitter regulation
Sox9	75.21	64.81	73.58	76.23	Gene regulation + RNA binding
Sparcl1	76.75	99.65	71.70	97.10	ECM + adhesion
Syt11	85.64	73.87	85.85	60.99	Miscellaneous
Timp3	71.28	74.39	33.49	42.55	ECM + adhesion
Tmem47	77.61	83.28	75.00	87.22	ECM + adhesion
Tpcn1	39.32	30.14	30.19	17.91	Ion + neurotransmitter regulation
Tsc22d4	86.32	92.51	68.40	76.38	Gene regulation + RNA binding
Tspan7	97.78	99.13	89.62	96.42	ECM + adhesion
Ttyh1	91.28	97.21	77.83	97.14	Ion + neurotransmitter regulation

Shown are the 94 shared adult dormant NSC genes, and the relative proportions of juvenile/adult V-SVZ and SGZ NSCs and astrocytes that detectably express these genes. The astrocytes in this analysis included the green cells in Figures 1B (SGZ) and 2E (V-SVZ). The shared genes were also categorized with regard to a number of broad cellular processes including metabolism, cell signaling, ion and neurotransmitter regulation, cell adhesion and the extracellular matrix (ECM), gene regulation and RNA binding, and detoxification.