Table 2

Group comparisons analysis of data from this study

NMean ± SEMp value
Figure 2One-way ANOVA followed by Tukey’s multiple comparisons test
2AZT3–ZT9 SLEEP13165 ± 120.5226, daytime compared with nighttime
ZT15–ZT21 saline11139 ± 11
ZT15–ZT21 glucose13302 ± 22<0.0001, glucose compared with no glucose
2BZT3–ZT9 SLEEP6133 ± 140.5515, daytime compared with nighttime
ZT15–ZT21 saline6101 ± 8
ZT15–ZT21 glucose6294 ± 33<0.0001, glucose compared with no glucose
2DZT3–ZT9 SLEEP117 ± 10.9851, daytime compared with nighttime
ZT15–ZT21 saline108 ± 1
ZT15–ZT21 glucose1022 ± 60.0352, glucose compared with no glucose
2EZT3–ZT9 SLEEP116 ± 10.8985, daytime compared with nighttime
ZT15–ZT21 saline108 ± 1
ZT15–ZT21 glucose1023 ± 60.0116, glucose compared with no glucose
Figure 3Unpaired t test
3AGlucose + saline12311 ± 170.0289
Glucose + MK80112370 ± 19
3BGlucose + saline1114 ± 20.0363
Glucose + MK8011123 ± 4
3CGlucose + saline1112 ± 10.0075
Glucose + MK8011123 ± 4
Figure 4Two-way repeated-measures ANOVA matching blood glucose from the same animal, which was
followed by Tukey’s multiple comparisons test
BaselineSaline7178 ± 12>0.05, compared with saline group
AP57193 ± 10
MK8017191 ± 8
CPP6190 ± 17
Post-NMDAR blockerSaline7175 ± 9
AP57192 ± 170.7902, compared with saline group
MK8017223 ± 100.0163, compared with saline group
CPP6195 ± 180.7456, compared with saline group
PostglucoseSaline7345 ± 9
AP57334 ± 250.9746, compared with saline group
MK8017434 ± 10<0.0001, compared with saline group
CPP6372 ± 110.2813, compared with saline group
Figure 5Unpaired t test
5AGlucose + saline19299 ± 130.0005
Glucose + ketamine18380 ± 17
5BGlucose + saline168 ± 10.0446
Glucose + ketamine1615 ± 3
5CGlucose + saline169 ± 10.0217
Glucose + ketamine1616 ± 3
Figure 6Unpaired t test
6ADiabetic + saline9290 ± 130.0001
Diabetic + MK8019403 ± 18
6BDiabetic + saline98 ± 20.0454
Diabetic + MK801918 ± 4
6CDiabetic + saline98 ± 20.0469
Diabetic + MK801918 ± 4