Method | Parameter | Sample size | Number of measurements for each observer | Median [IQR] | Student’s paired t test | |||||
---|---|---|---|---|---|---|---|---|---|---|

Observer 1 | Observer 2 | t | p value | |||||||

cTMS | A-SICI_{1ms} | 18 | 18 | 16.6 [23.2] | 15.9 [21.8] | 2.11 | 0.45 | |||

A-SICI_{2.5ms} | 18 | 18 | 25.3 [23.8] | 40.8 [35.1] | 2.11 | 0.0103 | ||||

A-SICI_{3ms} | 18 | 18 | 43.3 [33.1] | 33.7 [35.4] | 2.11 | 0.89 | ||||

A-SICI_{1-3.5ms} | 18 | 108 | 42.2 [27.1]^{b} | 31.5 [16.5]^{b} | 2.11 | 0.63 | ||||

A-SICI_{1-7ms} | 18 | 162 | 61.4 [38.2]^{b} | 44.3 [21.4]^{b} | 2.11 | 0.74 | ||||

RMT_{0.2mV} | 18 | 18 | 54.3 [8.4] | 53.9 [8.8] | 2.11 | 0.73 | ||||

TS_{1mV} | 18 | 18 | 65.9 [12.3] | 64.5 [14.1] | 2.11 | 0.46 | ||||

Mean (±SE)^{a} | SD | Mean (±SE)^{a} | SD | |||||||

TT-TMS | T-SICI_{1ms} | 18 | 18 | 9.4 (±2.01) | 8.9 | 10.5 (±1.58) | 6.7 | 2.11 | 0.49 | |

T-SICI_{2.5ms} | 18 | 18 | 9.4 (±2.49) | 10.6 | 6.8 (±1.89) | 8.0 | 2.11 | 0.28 | ||

T-SICI_{3ms} | 18 | 18 | 5.5 (±2.43) | 10.3 | 6.9 (±2.45) | 10.4 | 2.11 | 0.47 | ||

T-SICI_{1-3.5ms} | 18 | 108 | 6.2 (±1.53) | 6.5 | 6.2 (±1.44) | 6.1 | 2.11 | 0.98 | ||

T-SICI_{1-7ms} | 18 | 162 | 3.1 (±1.65) | 7.0 | 3.6 (±1.37) | 5.8 | 2.12 | 0.82 | ||

RMT_{0.2mV} | 18 | 18 | 54.5 (±1.96) | 8.3 | 54.4 (±2.03) | 8.6 | 2.11 | 0.84 |

Reproducibility of interobserver measurements of A-SICI and T-SICI. Sample size

*n*= 18 for cTMS and TT-TMS for observer 2. Calculation of statistical parameters is based on TMS measurements from observer 2 (from one TMS measurement for each subject) and the corresponding examination (by session, first examination in the session) by observer 1. A significant difference between observers was seen in A-SICI_{2.5ms}(*p*= 0.0103) only. Differences were interpreted as significant at*p*< 0.05.↵a Normally distributed data were arithmetically averaged to calculate mean (±SE) and SD.

↵b Point estimates for each subject were calculated as geometric means of their measurements. Data are displayed as medians with interquartile ranges [IQR] of subjects’ point estimates.