Table 1

Definitions of ROIs drawn manually to delineate WM tracts

TractInclusion ROI 1Inclusion ROI 2Exclusion ROI
UFEntire temporal lobe identified in coronal plane at level where frontal and temporal lobe are no longer connectedAll projections into frontal lobeFibers which project into anterior limb of external capsule and posteriorly
IFOFOccipital lobe selected in coronal plane identified halfway between posterior edge of cingulum and posterior of the brainEntire hemisphere in coronal plane at level of the genu of CC identified in mid-sagittal sliceFibers crossing medially through anterior commissure
ILFEntire hemisphere selected in coronal plane at posterior edge of cingulum identified at mid-sagittal sliceEntire temporal lobe identified in the coronal plane at level where frontal and temporal lobe are no longer connectedFibers that track medially into fornix and CC
SLFIdentified in coronal plane at lowest axial level in which fornix can be identified as a single structureProjections passing through coronal plane at level of splenium of CC identified in mid-sagittal sliceFiber that project into external capsule
  • UF, uncinate fasciculus; IFOF, inferior fronto-occipital fasciculus; ILF, inferior longitudinal fasciculus; SLF, superior longitudinal fasciculus; CC, corpus callosum.