A Summary outlining the onset of Opn3-eGFP expression in various structures of the CNS and PNS, indicating novel Opn3-eGFP+ structures identified in this study (•)
| PNS and sensory organs | CNS | Age | |
|---|---|---|---|
| Trigeminal ganglion • | Neural tube | Basal plate | E9.5 |
| Facio-acoustic complexganglion • | Brainvesicles | Basal plate of diencephalon | |
| Olfactory placode | Dorsal outer cells of mesencephalon | ||
| Dorsal root ganglion | Spinal cord | Motor neurons | E10.5 |
| Inferior vagus ganglion • | |||
| Glossopharyngealganglion • | Brainvesicles | Optic stalk | |
| Migratory olfactoryneurons | |||
| Retinal ganglion cells | Spinal cord | Dorsal, lateral and ventral mantleand marginal layers | E13.5 |
| Optic nerve | |||
| Olfactory epithelium • | Hindbrain | Spinal trigeminal nucleus • | |
| Olfactory nerve • | Principal sensory trigeminal nucleus • | ||
| Vomeronasal organ • | Mesencephalic trigeminal nucleus • | ||
| Vomeronasal nerve • | Genu of facial nerve • | ||
| Solitary tract | |||
| Parabrachial nuclei • | |||
| Hypoglossal nucleus • | |||
| Nucleus prepositus • | |||
| Vestibular nuclei • | |||
| Medial longitudinal fasciculus | |||
| Abducens nucleus • | |||
| Cochlear nuclei • | |||
| Superior olivary complex | |||
| External granular layers of cerebellum | |||
| Deep cerebellar nuclei | |||
| Superior cerebellar peduncle | |||
| Midbrain | Red nucleus | ||
| Oculomotor associated sub nuclei • | |||
| Tegmental fibres | |||
| Forebrain | Subthalamic area | ||
| Dorsal thalamus | |||
| Dorsal medial hypothalamic nucleus | |||
| Stria medullaris | |||
| Optic tract | |||
| Olfactory bulb | |||
| Pinna of the ear | Hindbrain | Medullary reticular nuclei | E15.5 |
| Magnocellular reticular nucleus | |||
| Raphe obscurus • | |||
| Cuneate and gracile nuclei • | |||
| Pontine nuclei | |||
| Medial cerebellar peduncle • | |||
| Motor trigeminal nucleus | |||
| Nucleus of lateral lemniscus | |||
| Brachium of inferior colliculus | |||
| Midbrain | Midbrain reticular nuclei | ||
| Inferior colliculus | |||
| Brachium of inferior colliculus | |||
| Forebrain | Periventricular thalamic nucleus | ||
| Dorsal lateral geniculate nucleus | |||
| Septal nuclei • | |||
| Paraventricular hypothalamic nucleus | |||
| Cerebellum | Uncinate fasciculus of cerebellum | E17.5 | |
| Midbrain | Periaqueductal gray • | ||
| Cuneiform nucleus | |||
| Rubrospinal tract | |||
| Substantia nigra | |||
| Epithalamus | Pineal gland | ||
| Thalamus | Parafascicular nucleus • | ||
| Ventromedial thalamic nucleus | |||
| Subthalamus | Subthalamic nucleus | ||
| Hypothalamus | Periventricular hypothalamic nucleus | ||
| Medial hypothalamic nucleus | |||
| Cerebrum | Subfornical organ | ||
| Nucleus accumbens | |||
| Pyriform cortex | |||
| Thalamus | Posterior thalamus | P0.5 | |
| Lateral dorsal nucleus | |||
| Ventral posteromedial nucleus | |||
| Ventral posterolateral nucleus | |||
| Subpallium | Dentate gyrus of hippocampus | ||
| Pallium | Anterior cingulate cortex | ||
| Frontal cortex | |||
| Hypothalamus | Mammillary nuclei | P10 | |
| Posterior nucleus | |||
| Subpallium | Fornix | ||
| Subiculum | |||
| Corticostrial circuitry | |||
| Meninges | Outer membrane | ||
| Hypothalamus | Perifornical nuclei | Adult | |
| Tanycytes | |||
| Supraoptic nucleus | |||
| Bed nucleus of stria terminalis | |||