ROIs Denoted by AAL area expressing the greatest integrated positive change for longitudinal measurements
| Coordinates | ||||||||
|---|---|---|---|---|---|---|---|---|
| Domain | Age group | x | y | z | AAL region | Hem | Integral | N. ROIs |
| MEM | Young | −3 | 30 | −6 | Cingulate gyrus (Ant) | L | 220.34 | 71 |
| 3 | 33 | −6 | Cingulate gyrus (Ant) | R | 213.26 | 35 | ||
| 9 | 36 | −9 | Superior frontal gyrus (MedOrb) | R | 212.14 | 9 | ||
| Middle | −3 | 42 | −6 | Superior frontal gyrus (MedOrb) | L | 142.20 | 10 | |
| −9 | 48 | −3 | Cingulate gyrus (Ant) | L | 141.01 | 66 | ||
| 3 | 33 | −6 | Cingulate gyrus (Ant) | R | 136.41 | 32 | ||
| Old | 15 | −15 | −24 | Undefined | R | 132.92 | 302 | |
| 15 | −9 | −15 | Hippocampus | R | 99.99 | 9 | ||
| −15 | −6 | −12 | Hippocampus | L | 93.77 | 41 | ||
| FLUID | Young | −21 | 63 | 9 | Superior frontal gyrus (DL) | L | 534.51 | 49 |
| −9 | 63 | 12 | Superior frontal gyrus (Med) | L | 388.11 | 85 | ||
| −27 | 57 | 12 | Middle frontal gyrus (MedOrb) | L | 369.12 | 57 | ||
| Middle | −21 | 63 | 9 | Superior frontal gyrus (DL) | L | 340.66 | 41 | |
| −9 | 63 | 12 | Superior frontal gyrus (Med) | L | 282.29 | 91 | ||
| 15 | −93 | −12 | Lingual gyrus | R | 241.39 | 30 | ||
| Old | 24 | −93 | −12 | Lingual gyrus | R | 254.76 | 18 | |
| 27 | −90 | −9 | Inferior occipital lobe | R | 221.99 | 23 | ||
| 15 | 63 | 15 | Superior frontal gyrus (Med) | R | 188.51 | 46 | ||
| SPEED | Young | −6 | 45 | −9 | Superior frontal gyrus (MedOrb) | L | 265.70 | 10 |
| −6 | 39 | −6 | Cingulate gyrus (Ant) | L | 236.82 | 105 | ||
| 6 | 39 | −9 | Superior frontal gyrus (MedOrb) | R | 223.88 | 8 | ||
| Middle | −6 | 45 | −6 | Superior frontal gyrus (MedOrb) | L | 204.89 | 10 | |
| 18 | −96 | −3 | Calcarine fissure + surrounding cortex (V1) | R | 201.23 | 31 | ||
| −9 | 48 | −3 | Cingulate gyrus (Ant) | L | 194.51 | 97 | ||
| Old | 24 | −42 | −33 | Undefined | R | 117.47 | 145 | |
| 18 | −96 | −3 | Calcarine fissure + surrounding cortex (V1) | R | 111.69 | 14 | ||
| −6 | 51 | 6 | Superior frontal gyrus (Med) | L | 105.11 | 39 | ||
| VOCAB | Young | 30 | −90 | 9 | Middle occipital lobe | R | 375.25 | 88 |
| 15 | −96 | 3 | Calcarine fissure + surrounding cortex (V1) | L | 355.38 | 31 | ||
| 33 | −90 | 0 | Inferior occipital lobe | R | 336.67 | 85 | ||
| Middle | 30 | −90 | 9 | Middle occipital lobe | R | 349.44 | 88 | |
| 15 | −96 | 3 | Calcarine fissure + surrounding cortex (V1) | R | 333.87 | 31 | ||
| 33 | −90 | 0 | Inferior occipital lobe | R | 310.89 | 81 | ||
| Old | 15 | −96 | 3 | Calcarine fissure + surrounding cortex (V1) | R | 252.60 | 30 | |
| 30 | −90 | 9 | Middle occipital lobe | R | 242.30 | 71 | ||
| 33 | −90 | 0 | Inferior occipital lobe | R | 205.04 | 79 | ||
The three regions per age bracket and domain displaying the greatest integrated positive change at the >97.5 percentile, are presented. Integrated change was calculated via trapezoidal summation in the segmented age bracket. Coordinates refer to the left voxel of the ROI. Higher values signify greater positive change. The “N.ROIs” column represents the number of ROIs in the >97.5 percentile subset (601 ROIs/comparison) for which the center voxel is located in the AAL (automated anatomical labeling) region listed. For instance, in the case of the first row entry, the left anterior cingulate gyrus displayed the greatest positive change at x, y, and z locations (−3, 30, and −6), but this region was among the top 601 ROIs displaying the greatest positive change for 71 of the 601 ROIs. Hem, Hemisphere; L, left; R, right; DL, dorsolateral; Med, medial; Ant, anterior; Med, medial.