Table 4

Proportion of the different synaptic shapes in Layers II and III of the EC

EC
layer
GroupType of
synapse
Macular
synapses
Perforated
synapses
Horseshoe
synapses
Fragmented
synapses
Total
synapses
IIControlAS83.0% (1285)12.9% (200)3.3% (51)0.8% (13)100% (1549)
SS73.0% (100)11.0% (15)15.3% (21)0.7% (1)100% (137)
AlzheimerAS80.6% (769)13.4% (128)4.9% (47)1.1% (10)100% (954)
SS73.4% (66)12.2% (11)12.2% (11)2.2% (2)100% (90)
IIIControlAS75.9% (1326)19.9% (347)3.3% (58)0.9% (15)100% (1746)
SS65.9% (85)15.5% (20)17.0% (22)1.6% (2)100% (129)
AlzheimerAS82.8% (806)10.2% (99)4.3% (42)2.7% (26)100% (973)
SS73.9% (68)8.7% (8)10.9% (10)6.5% (6)100% (92)
  • Data are given as percentages with the absolute number of synapses studied in parentheses. Data for individual cases are shown in Extended Data Table 4-1, Table 4-2.