Membrane properties of CA1 pyramidal cells after exposure to Tat and morphine
| In vivo treatment | Tat− Vehicle n = 13 | Tat+ Vehicle n = 12 | Tat− Morphine n = 19 | Tat+ Morphine n = 13 | Tat− Morphine n = 29 | Tat+ Morphine n = 22 |
|---|---|---|---|---|---|---|
| Ex vivo treatment | - | - | Morphine | Morphine | - | - |
| Capacitance (pF) | 130.2 ± 12.4 | 175.4 ± 16.0 | 157.7 ± 9.5 | 138.4 ± 10.3 | 166.3 ± 8.8 | 184.7 ± 13.5 |
| Resistance (MΩ) | 182.1 ± 21.6 | 154.7 ± 16.9 | 146.4 ± 10.2 | 127.2 ± 8.9 | 179.0 ± 10.9 | 149.2 ± 16.2 |
Capacitance and resistance values from pyramidal cell recordings from Tat− and Tat+ mice maintained on vehicle (control)-containing or morphine (25 mg)-containing time-release implants in which morphine (500 nm) was present (“morphine”) or withheld (-) during recordings in hippocampal slices ex vivo. No significant changes were observed. All values are shown as the mean ± SEM.