Parameter | Symbol | Rho+/+ (RhoP23H/+ control) | RhoP23H/+ | Rho+/+ (Rho+/− control) | Rho+/− |
---|---|---|---|---|---|
Scaling constant* | K0 | 750 | 675 | 1100 | 990 |
Relative ONL thickness | fONL | 1 | 0.6 | 1 | 1 |
Dominant time constant | τ (s) | 0.135 | 0.055 | 0.138 | 0.068 |
Irradiance at half maximal output | EC50 (ph/μm2/s) | 300 | 300 | 300 | 300 |
Rod length | L (μm) | 24 | 12 | 24 | 24 |
Rod diameter | d (μm) | 1.4 | 1.4 | 1.4 | 1.4 |
Quantum efficiency | q | 0.63 | 0.63 | 0.63 | 0.63 |
Funneling | fp | 1.2 | 1.2 | .1.2 | 1.2 |
Pigment optical density | ΔD (od units/μm) | 0.019 | 0.019 | 0.019 | 0.0095 |
*K0 @12Hz = 0.6×K0 |
Model parameters for the model fits depicted in Figure 5. All parameters were measured in this study (ONL thickness, Fig. 1; τ, Fig. 7) or obtained from the literature (see Table 1).