Table 1

AP and passive membrane properties

Glutamatergic neuronsGABAergic neurons
Control,
n = 58
Fitful,
n = 48
p value95% CI of
difference
Control,
n = 36
Fitful,
n = 48
p value95% CI of
difference
V(rest) (mV)−61.3 ± 2.06−61.5 ± 2.080.871−2.33 to 2.75−61.5 ± 2.12−61.9 ± 2.070.739−2.1 to 2.96
AP threshold (mV)−37.5 ± 1.0−36.4 ± 0.990.215−2.78 to 0.62−39.2 ± 1.1−39.3 ± 1.00.840−1.61 to 1.97
AP half-width (ms)2.5 ± 0.122.5 ± 0.120.986−0.3 to 0.31.41 ± 0.071.44 ± 0.070.71−0.13 to 0.2
AP Peak (mV from 0)26.2 ± 1.7123.2 ± 1.570.074−6.29 to 0.2930.84 ± 2.1227.24 ± 1.750.065−7.41 to 0.2
AHP amp. (mV)−53.0 ± 1.11−53.9 ± 1.160.424−1.26 to 3.06−59.2 ± 1.32−60.6 ± 1.260.273−1.05 to 3.74
Control,
n = 31
Fitful,
n = 30
p
value
95% CI of
difference
Control,
n = 40
Fitful,
n = 52
p
value
95% CI of
difference
Resistance (MΩ)218.2 ± 21.2195.0 ± 19.00.384−75.4 to 29.0197.3 ± 17.6209.1 ± 16.90.580−30.0 to 53.6
Capacitance (pF)99.76 ± 11.34114.46 ± 12.910.249−10.3 to 39.7102.89 ± 11.3492.43 ± 9.580.267−28.93 to 8.0
  • Mean ± SEM for each of the measures parameters; p values and 95% CIs were derived from pairwise comparisons of the estimated marginal means from GEEs.