Overview of the studies
| Study 1 | Study 2 | Study 3 | Study 4 | Study 5 | |
|---|---|---|---|---|---|
| Animals | Female Fischer 344 | Male Wistar | Female Fischer 344 | Female Wistar | Female Fischer 344 |
| SCI | Th8/9 Contusion Mod. and Mod.Sev (150 kDyn) | Th8 Contusion Mod.Sev. (200 kDyn) | Th8 Contusion Mod.Sev. (200 kDyn) | Th8/9 Dorsal Hemisection Scouten wire-knife transection | C4 bilateral dorsal column tungsten wire-knife transection |
| Time points of gait assessment | UI, 60 dpi | UI, 7, 30, 60 dpi | UI, 15, 22, 29, 36, 43 dpi | UI, 30, 60 dpi | UI, 30 dpi |
| CatWalk system | CatWalk XT | CatWalk 7.1 | CatWalk XT | CatWalk XT | CatWalk XT |
| Groups | UI Veh.Mod Veh.Mod.-Sev Exp.Mod Exp.Mod.-Sev. | UI SCI+Veh. SCI+Prog. | Young SCI Old SCI | UI SCI Veh. | UI SCI Veh. |
UI: uninjured; Prog.: progesterone; Mod.: Moderate; Sev.: severe; Veh.: vehicle; Exp.: experiment.