Table 3

Passive and active physiological properties of stellate and pyramidal PrCs

SCsPCsp value
Passive properties
    Resting membrane potential (mV)−59.4 ± 0.8 (22)−62.0 ± 1.2 (23)0.06
    Input resistance (MΩ)94.3 ± 11.6 (22)162.0 ± 20.0 (23)<0.01
    Membrane time constant (ms)13.3 ± 0.8 (21)23.7 ± 2.4 (20)<0.001
    Membrane capacitance (pF)185.7 ± 23.4 (20)209.5 ± 35.5 (21)0.51
Active properties
    Rheobase (pA)90.9 ± 10.2 (22)89.1 ± 11.7 (23)0.91
    Voltage threshold (mV)−39.8 ± 0.8 (22)−41.7 ± 1.0 (23)0.28
    AP amplitude (mV)*78.1 ± 1.6 (22)83.8 ± 1.9 (23)<0.05
    AP maximum rise rate (mV/ms)346.1 ± 19.4 (22)433.3 ± 31.8 (23)<0.05
    AP maximum decay rate (mV/ms)111.1 ± 19.1 (22)81.8 ± 3.8 (23)0.15
    Half-height duration (ms)0.92 ± 0.03 (22)1.11 ± 0.05 (23)<0.05
    Fast AHP amplitude (mV)*−10.7 ± 0.4 (22)−10.4 ± 0.6 (23)0.65
    Discharge frequency at 250 pA (Hz)34.0 ± 2.9 (22)39.7 ± 2.6 (23)0.15
    Voltage sag (mV)**−9.2 ± 0.8 (38)−6.3 ± 0.8 (32)<0.05
    ISI ratio**0.36 ± 0.05 (38)0.61 ± 0.05 (32)<0.01
    dAP (mV)**2.4 ± 0.3 (38)1.6 ± 0.3 (32)0.13
    Latency to first AP at 205 pA (ms)**19.6 ± 3.3 (38)46.8 ± 8.4 (32)<0.01

  • Results shown as mean ± SEM, number of analyzed neurons shown in parenthesis. Parameters used for the principal component analysis are highlighted with a double asterisk.

  • ↵* Measured from threshold.

  • ↵** Parameter used for PCA. ISI ratio was calculated from the first and the second interval.