Table 2

A table of all of the statistical tests and associated result

DataFigureStatistical testTest valuesp value
0 min, all conditions, RMP4Kruskal–Wallis ANOVAH(4) = 0.5385p = 0.4657
0 min, all conditions, IR4Kruskal–Wallis ANOVAH(4) = 2.109p = 0.2727
0 min all conditions, FR4Kruskal–Wallis ANOVAH(4) = 1.395p = 0.8511
0 vs 32 min, α-syn aggregates, IR4Wilcoxon signed-rank testW(+) = 2.0, W(–) = 64.0, Z = 2.7p = 0.0029
0 vs 32 min, α-syn monomers, IR4Wilcoxon signed-rank testW(+) = 6.5, W(–) = 14.5, Z = 0.73p = 0.4688
0 vs 32 min, vehicle, IR4Wilcoxon signed-rank testW(+) = 46.0, W(–) = 9.0, Z = −1.83p = 0.0645
32 min, α-syn aggregates, α-syn monomers and vehicle, IR4Kruskal–Wallis ANOVAH(2) = 14.53p = 0.0007
16 min, α-syn aggregates, α-syn monomers and vehicle, IR4Kruskal–Wallis ANOVAH(2) = 10.67p = 0.0048
0 vs 32 min, vehicle, RMP4Wilcoxon signed-rank testW(+) = 41.5, W(–) = 3.5, Z = −2.19p = 0.0234
0 vs 32 min, α-syn aggregates, RMP4Wilcoxon signed-rank testW(+) = 61.0, W(–) = 5.0, Z = −2.44p = 0.0107
0 vs 32 min, α-syn monomers, RMP4Wilcoxon signed-rank testW(+) = 19.5, W(–) = 1.5 Z = −1.79p = 0.0938
32 min, α-syn aggregates, α-syn monomers and vehicle, RMP4Kruskal–Wallis ANOVAH(2) = 2.234p = 0.3273
0 vs 32 min, vehicle, FR4Wilcoxon signed-rank testW(+) = 14, W(–) = 41.0 Z = −1.32p = 0.1895
0 vs 32 min, α-syn aggregates, FR4Wilcoxon signed-rank testW(+) = 1.0, W(–) = 65.0 Z = 2.8p = 0.0020
0 vs 32 min, α-syn monomers, FR4Wilcoxon signed-rank testW(+) = 11, W(–) = 10.0 Z = 0p > 0.9999
32 min, α-syn aggregates, α-syn monomers and vehicle, FR4Kruskal–Wallis ANOVAH(2) = 10.21p = 0.0061
0 min, all conditions, capacitance5Kruskal–Wallis ANOVAH(4) = 6.269p = 0.18
0 vs 32 min, α-syn aggregates, membrane conductance5Wilcoxon signed-rank testW(+) = 66.0 , W(–) = 0 Z = −2.89p = 0.001
0 vs 32 min, vehicle, membrane conductance5Wilcoxon signed-rank testW(+) = 71.0 , W(–) = 7 Z = −2.47p = 0.009
32 min, α-syn monomers and vehicle, membrane conductance5Mann–Whitney testVehicle median = 2.820, n = 12, α-syn monomers = 2.820,
n = 6, U = 36		p > 0.9999
32 min, α-syn aggregates and vehicle, membrane conductance5Mann–Whitney testα-Syn aggregates median = 6.450, n = 11, vehicle median = 2.820,
n = 12, U = 11		p = 0.0003
0 min, vehicle and vehicle + glib, RMP6Mann–Whitney testVehicle median = −56, n = 10, vehicle + glib median = −54, n = 6,
U = 21.50		p = 0.3791
0 min, vehicle and vehicle + glib, IR6Mann–Whitney testVehicle median = 338.3, n = 10, vehicle + glib median = 393, n = 6,
U = 18.50		p = 0.2294
0 min, vehicle and vehicle + glib, FR6Mann–Whitney testVehicle median = 69.5, n = 10, vehicle + glib median = 86.5, n = 6,
U = 25.50		p = 0.6548
0 vs 32 min, vehicle + glib, IR6Wilcoxon signed-rank testW(+) = 9.0, W(–) = 12.0 Z = 0.21p = 0.8438
0 vs 32 min, vehicle + glib, FR6Wilcoxon signed-rank testW(+) = 7.0, W(–) = 14.0 Z = 0.63p = 0.5625
0 vs 32 min, α-syn + glib, IR6Wilcoxon signed-rank testW(+) = 5.0, W(–) = 16.0 Z = 1.04p = 0.25
0 vs 32 min, α-syn + glib, FR6Wilcoxon signed-rank testW(+) = 7.0, W(–) = 14.0 Z = 0.63p = 0.353
0 vs 32 min, α-syn + glib, membrane conductance7Wilcoxon signed-rank testW(+) = 21.0, W(–) = 0 Z = 0.63p = 0.0313
32 min, vehicle + glib and α-syn + glib, membrane conductance7Mann–Whitney testVehicle + glib median = 4.675, n = 6, α-syn + glib median = 3.33,
n = 6, U = 11		p = 0.3095
Normalized conductance over time, all conditions
Conductance effect
Time effect
α-Syn aggregates vs control
α-Syn aggregates vs monomers
α-Syn aggregates vs vehicle + glib
α-Syn aggregates vs α-syn + glib		7Kruskal–Wallis ANOVA
Dunn’s post hoc analysis		F(4,180) = 6.806
F(4,180) = 11.01		p < 0.0001
p < 0.0001
p < 0.0001
p = 0.0003
p < 0.0001
p = 0.0045